Defiance Vacation Packages

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Flight and hotel packages to Defiance

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Save 100% on your flight
per person
Jul 19 - Jul 22
Roundtrip non-stop flight included
Charlotte (CLT) to St. Louis (STL)
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the spa tub and free perks like continental breakfast and free self parking.
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
per person
Jul 19 - Jul 22
Roundtrip non-stop flight included
Charlotte (CLT) to St. Louis (STL)
This luxury hotel features a casino, a full-service spa, and 5 restaurants. Enjoy the 2 spa tubs and 24-hour gym, and unwind with a drink at the poolside bar.
River City Casino & Hotel

River City Casino & Hotel

4 out of 5
per person
Jul 25 - Jul 29
Roundtrip non-stop flight included
Salt Lake City (SLC) to St. Louis (STL)
This hotel features a casino, a nightclub, and 5 restaurants. Traveling on business? Take advantage of the business center, conference center, and conference space. Enjoy the 24-hour gym and perks like free self parking.
The Pennywell St.Louis Downtown, a Hilton Hotel

The Pennywell St.Louis Downtown, a Hilton Hotel

4 out of 5
Downtown St. Louis
per person
Jul 25 - Jul 29
Roundtrip non-stop flight included
Salt Lake City (SLC) to St. Louis (STL)
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the express check-in, express check-out, and valet parking. Self parking, dry cleaning, and luggage storage are also offered.
The Charles F. Knight Center

The Charles F. Knight Center

2.5 out of 5
per person
Jul 25 - Jul 29
Roundtrip non-stop flight included
Salt Lake City (SLC) to St. Louis (STL)
This hotel features 3 restaurants and a bar/lounge. WiFi in public areas is free. Self parking and a coffee shop are also offered on site.

Top Defiance hotel deals

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Free Cancellation
Reserve now, pay when you stay
The price is $130 per night
$130
per night
Jun 9 - Jun 10
A casino, 7 restaurants, and a 24-hour gym are all featured at this hotel. Traveling for business? Take advantage of the 24-hour business center, express check-out, and conference space. Relax with a drink at one of the 3 bars/lounges and enjoy perks like free self parking.
Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield

3 out of 5
15431 Conway Rd, Chesterfield, MO
Free Cancellation
Reserve now, pay when you stay
The price is $100 per night
$100
per night
May 29 - May 30
A full-service spa and a 24-hour gym are featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and free perks like continental breakfast and free self parking. A business center, free WiFi in public areas, and a garden are also on offer.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
2801 Fountain Pl, Wildwood, MO
Free Cancellation
Reserve now, pay when you stay
The price is $90 per night
$90
per night
Jun 18 - Jun 19
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the spa tub and free perks like continental breakfast and free self parking.
La Quinta Inn & Suites by Wyndham St. Louis Westport

La Quinta Inn & Suites by Wyndham St. Louis Westport

2.5 out of 5
11805 Lackland Rd, Maryland Heights, MO
Free Cancellation
Reserve now, pay when you stay
The price is $76 per night
$76
per night
May 28 - May 29
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Guests will appreciate freebies like self-serve breakfast and free self parking.
Pet friendly
Breakfast included
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd, St. Charles, MO
Free Cancellation
Reserve now, pay when you stay
The price is $169 per night
$169
per night
May 27 - May 28
This luxury hotel features a casino, a full-service spa, and 5 restaurants. Enjoy the 2 spa tubs and 24-hour gym, and unwind with a drink at the poolside bar.
Crowne Plaza St. Louis Airport, an IHG Hotel

Crowne Plaza St. Louis Airport, an IHG Hotel

3.5 out of 5
11228 Lone Eagle Dr, Bridgeton, MO
Free Cancellation
The price is $121 per night
$121
per night
May 27 - May 28
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Enjoy the gym and perks like a free area shuttle.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit in Defiance

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St. Louis Union Station

4/5(615 reviews)

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.

St. Louis Union Station
Image for Gateway Arch

Gateway Arch

4.5/5(2,511 reviews)

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch
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St. Louis Zoo

4.5/5(1,212 reviews)

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

St. Louis Zoo

Photos of local treasures

Defiance

Frequently asked questions

How much are vacation packages to Defiance?
Adventure awaits in Defiance, with Travelocity vacation packages starting from just $512. In addition to flights and hotels, these awesome deals make it a breeze to see every corner of the globe.
Where can I get the best vacation package deals for Defiance?
It’s hard to look past Travelocity when it comes to putting together your Defiance package deal. There are as many as 400 air carriers and 1,000,000 properties worldwide to select from. Reserve your trip now and get ready to cross another destination off your list.
Why should I book my Defiance vacation package with Travelocity?
Whether you’re searching for the ultimate unplugged escape or you crave the hustle and bustle that only a big city can provide, booking everything with Travelocity saves you time, hassle and money. No need to sift through countless websites to find the best deal — our Price Match Guarantee ensures you’ll always get the lowest possible price, and our team of customer service experts are available 24/7 should you need them.
Will I save money on my Defiance car rental if I book it with hotels and flights?
You certainly can — combine your car, hotel and flight into a Defiance vacation package and you can save plenty. With so many things to do in Defiance, having your own set of wheels will make exploring easy. Once you’ve settled into the driver’s seat, hit the wide open road and head toward Busch Stadium, a renowned attraction about 30 mi from Defiance.
What is the best time of year to go to Defiance?
Consider visiting in March, April and May if you like being in the thick of things. Even though they’re the busiest few months, the buzz of the tourist season is almost impossible to resist. If you’re chasing a calmer pace, December, January and February will suit you better. Don’t want to pay big bucks for your digs? Avoid booking in , when rates usually soar. Search for something affordable in instead.
Which airport is best for Defiance?
The top airport for Defiance is Lambert-St. Louis Intl. Airport (STL). It sits 25 mi west of the downtown area.
What is there to do in Defiance?
You’ll notice a particular magic in the air as you wander through the streets of Defiance. Historic Daniel Boone Home and Heritage Center and Chandler Hill Vineyards are just a couple of attractions that make this city such a sought-after destination, so add them to your list of places to see.
Where should I stay when visiting Defiance?
If you’re after a place to spend your nights, have a look at the The Reubling House - Modern-rustic Cabin!. It’s the top pick for many visitors.