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Featured Florida Keys 4 Star hotels

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Little Palm Island Resort & Spa - A Noble House Resort

Little Palm Island Resort & Spa - A Noble House Resort

4.5 out of 5.0 28500 Overseas Hwy, Little Torch Key, FL
5/5
(1 Reviews)
This luxury resort features a private beach, a full-service spa, and a marina. Traveling on business? Take advantage of the free WiFi in public areas and airport shuttle. Enjoy the outdoor pool and perks like free valet parking.
$332
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

4.0 out of 5.0 97000 Overseas Hwy, Key Largo, FL
4.3/5
(11 Reviews)
A private beach, 2 restaurants, and 2 outdoor pools are all featured at this smoke-free resort. Relax with sun loungers and beach umbrellas, and cool off with a drink at the beachside bar. Families will appreciate complimentary bicycles and free childcare.
$629
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

4.5 out of 5.0 1 Knights Key Boulevard, MM 47, Marathon, FL
4.2/5
(30 Reviews)
This smoke-free resort features a full-service spa, 5 outdoor pools, and a restaurant. Spend a day at the beach scuba diving, or relax with sun loungers and beach umbrellas. Relax with a drink at one of the 2 bars/lounges and get perks like free WiFi.
$459
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

4.0 out of 5.0 97450 Overseas Highway, Key Largo, FL
4.1/5
(12 Reviews)
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free resort. Relax with beach cabanas, sun loungers, and beach umbrellas. Enjoy the 24-hour fitness center and perks like free valet parking and free WiFi.
$269
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

4.0 out of 5.0 2600 Overseas Hwy, Marathon, FL
4/5
(22 Reviews)
This romantic resort features a private beach, 3 outdoor pools, and a restaurant. Relax beachside with sun loungers and cool off with a drink at the beach bar. Enjoy the fitness center and perks like free self parking and free WiFi.
$489
Cheeca Lodge & Spa

Cheeca Lodge & Spa

4.0 out of 5.0 81801 Overseas Highway, Mile Marker 82, Marker 82, Islamorada, FL
4/5
(20 Reviews)
This romantic resort features a private beach, a golf course, and a full-service spa. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. Families will appreciate the arcade/game room, picnic area, and supervised childcare.
$467
Hawks Cay Resort

Hawks Cay Resort

4.0 out of 5.0 61 Hawks Cay Blvd, Marathon, FL
3.7/5
(15 Reviews)
This romantic resort features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. There's fun for all ages with a children's pool and a playground, and families will appreciate the onsite laundry facilities.
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The Islands of Islamorada

The Islands of Islamorada

4.0 out of 5.0 82779 Old Hwy, Islamorada, FL
This villa's 2 outdoor pools and spa tub are among the featured amenities. Relax with a drink at the poolside bar and enjoy perks like free self parking and free WiFi. A garden, concierge services, and barbecue grills are also on offer.
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Duck Key - 2 Br Townhouse

Duck Key - 2 Br Townhouse

4.0 out of 5.0 5115 Sunset Village Dr, #158769, Marathon, FL
This vacation home features an outdoor pool and an outdoor tennis court. Enjoy the fitness center and perks like free self parking and free WiFi. A convenience store is also provided.
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Canal-front Dream W/ Private Pool, Spa & Dock 3 Bedroom Home

Canal-front Dream W/ Private Pool, Spa & Dock 3 Bedroom Home

4.0 out of 5.0 7515 Gulfstream Blvd, Marathon, FL
This vacation home features an outdoor pool and an outdoor tennis court. Enjoy the fitness center and perks like free self parking. A garden, a grocery/convenience store, and barbecue grills are also on offer.
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269charb 2 Bedroom Home

269charb 2 Bedroom Home

4.0 out of 5.0 269 Charlemagne Blvd, Key Largo, FL
This vacation home features an outdoor tennis court and a fitness center. Free self parking and barbecue grills are also offered on site.
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Canal-Side Getaway - 3 Br Home

Canal-Side Getaway - 3 Br Home

4.0 out of 5.0 185 Lorelane Pl, Key Largo, FL
This vacation home features an outdoor tennis court and a fitness center. Families will appreciate the playground and convenience store. Free self parking and barbecue grills are also offered on site.
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4 Star Hotels Florida Keys

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Florida Keys 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Florida Keys will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Florida Keys, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.


Recent Florida Keys hotel reviews by fellow wanderers


*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.