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Featured Florida Keys 4 Star Hotels

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Bungalows Key Largo - All Inclusive Resort, Adults Only

Bungalows Key Largo - All Inclusive Resort, Adults Only

4.0 out of 5.0 99010 Overseas Highway, Key Largo, FL
5/5
(1 Reviews)
This all-inclusive property features a private beach, a full-service spa, and 4 restaurants. Relax with free beach cabanas, sun loungers, and beach umbrellas. Enjoy the 2 outdoor pools and free perks like buffet breakfast and valet parking.
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Little Palm Island Resort & Spa - A Noble House Resort

Little Palm Island Resort & Spa - A Noble House Resort

4.5 out of 5.0 28500 Overseas Hwy, Little Torch Key, FL
5/5
(1 Reviews)
This luxury resort features a private beach, a full-service spa, and a restaurant. Traveling on business? Take advantage of the free WiFi in public areas and airport shuttle. Enjoy the outdoor pool and perks like free valet parking.
$326
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

4.0 out of 5.0 97000 Overseas Hwy, Key Largo, FL
4.3/5
(9 Reviews)
A private beach, 2 restaurants, and 2 outdoor pools are all featured at this resort. Families will appreciate the onsite laundry facilities and free childcare. Relax with a drink at one of the 2 bars/lounges and enjoy free perks like free self parking and WiFi in public areas.
$267
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

4.5 out of 5.0 1 Knights Key Boulevard, MM 47, Marathon, FL
4.2/5
(27 Reviews)
This smoke-free resort features a full-service spa, 5 outdoor pools, and a restaurant. Spend a day at the beach scuba diving, or relax with sun loungers and beach umbrellas. Relax with a drink at one of the 2 bars/lounges and get perks like free WiFi.
$287
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

4.0 out of 5.0 2600 Overseas Hwy, Marathon, FL
4.2/5
(42 Reviews)
This romantic resort features a private beach, 3 outdoor pools, and a restaurant. Relax beachside with sun loungers and cool off with a drink at the beach bar. Enjoy the fitness center and perks like free self parking and free WiFi.
$287
Cheeca Lodge & Spa

Cheeca Lodge & Spa

4.0 out of 5.0 81801 Overseas Highway, Mile Marker 82, Marker 82, Islamorada, FL
4.1/5
(50 Reviews)
This romantic resort features a private beach, a golf course, and a full-service spa. Families will appreciate the picnic area, kid-friendly dining, and supervised childcare. Enjoy the 2 outdoor pools and perks like free valet parking and free WiFi.
$332
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

4.0 out of 5.0 97450 Overseas Highway, Key Largo, FL
4.1/5
(12 Reviews)
This resort features 3 restaurants, an outdoor pool, and an outdoor tennis court. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. Enjoy the 24-hour fitness center and perks like free valet parking and free WiFi.
$359
Hawks Cay Resort

Hawks Cay Resort

4.0 out of 5.0 61 Hawks Cay Blvd, Marathon, FL
3.7/5
(32 Reviews)
This romantic resort features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. There's fun for all ages with a children's pool and a playground, and families will appreciate the onsite laundry facilities.
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Canal-Side Getaway - 3 Br Home

Canal-Side Getaway - 3 Br Home

4.0 out of 5.0 185 Lorelane Pl, Key Largo, FL
This vacation home features an outdoor tennis court and a fitness center. WiFi in public areas is free. A convenience store and barbecue grills are also provided.
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Waterfront luxury Villa (14) - 3 Br Townhouse

Waterfront luxury Villa (14) - 3 Br Townhouse

4.0 out of 5.0 11600 1st Avenue Gulf Villa 14, Marathon, FL
This villa features an outdoor pool and a fitness center. Barbecue grills are provided for your convenience.
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Shark Key Chateau Apartment 5

Shark Key Chateau Apartment 5

4.0 out of 5.0 79 Cannon Royal Drive, Key West, FL
Free WiFi in public areas is available at this villa.
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Waterfront luxury Villa (15) - 3 Br Townhouse

Waterfront luxury Villa (15) - 3 Br Townhouse

4.0 out of 5.0 11600 1st Avenue Gulf Villa 15, Marathon, FL
This vacation home features an outdoor pool and a fitness center. Barbecue grills are provided for your convenience.

Recently booked Florida Keys hotels

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4 Star Hotels Florida Keys

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Florida Keys 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Florida Keys will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Florida Keys, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Florida Keys Hotel Reviews By Fellow Wanderers

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.