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Featured San Francisco 4 Star Hotels

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Sortis Hotel, Spa & Casino, Autograph Collection

Sortis Hotel, Spa & Casino, Autograph Collection

4.5 out of 5.0 56 y 57 East Street, Obarrio, Bella Vista, Panama City, Panama
5/5
(1 Reviews)
This luxury hotel features a casino, a full-service spa, and 12 restaurants. Traveling on business? Take advantage of the 23 conference rooms, 24-hour business center, and airport shuttle. Enjoy the outdoor pool and perks like free WiFi.
$95
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

4.0 out of 5.0 Calle 50, Urb. Marbella, Panama City, Panama
4.9/5
(7 Reviews)
This eco-friendly hotel includes 3 restaurants, an outdoor pool, and a fitness center. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. There's a poolside bar on site, and laundry facilities and concierge services are also provided.
$73
Summit Rainforest & Golf Resort

Summit Rainforest & Golf Resort

4.0 out of 5.0 Omar Torrijos Ave, Paraiso, Panama Canal, Ancon, Panama
4.8/5
(5 Reviews)
A golf course, 3 restaurants, and 2 outdoor pools are all featured at this hotel. Bring the family and enjoy the children's pool, playground, and kid-friendly dining. Relax with a drink at one of the 2 bars/lounges and enjoy free perks like continental breakfast and an area shuttle.
$87
Panama Marriott Hotel

Panama Marriott Hotel

4.5 out of 5.0 52nd St. and Ricardo Arias, Panama City, Panama
4.7/5
(6 Reviews)
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 18 conference rooms, business center, and airport shuttle. Relax with a drink at one of the 2 bars/lounges and enjoy free perks like valet parking and WiFi in public areas.
$84
Marriott Executive Apartments Panama City, Finisterre

Marriott Executive Apartments Panama City, Finisterre

4.0 out of 5.0 Calle Colombia Y Ave.,3ra A Sur, Bella V, Panama City, Panama
4.7/5
(3 Reviews)
The aparthotel's outdoor pool, fitness center, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and airport shuttle. A restaurant, a 24-hour front desk, and a terrace are also provided.
$115
Hard Rock Hotel Panama Megapolis

Hard Rock Hotel Panama Megapolis

4.5 out of 5.0 Ave. Balboa al lado de Multicentro, Panama City, Panama
4.4/5
(7 Reviews)
This luxury hotel features a casino, a full-service spa, and a nightclub. There's fun for all ages with a children's club and a children's pool, and families will appreciate the onsite laundry facilities. Enjoy a meal in one of the 4 restaurants and perks like free WiFi.
$99
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

4.0 out of 5.0 Avenida Domingo Diaz via Tocumen, Centro Comercial MetroMall, San Miguelito, Panama
4.3/5
(7 Reviews)
This hotel features an outdoor pool, a fitness center, and a restaurant. Traveling on business? Take advantage of the 2 conference rooms, as well as the 24-hour business center and free WiFi in public areas. Unwind with a drink at the bar/lounge and enjoy perks like free self parking and a free shopping center shuttle.
$77
Wyndham Panama Albrook Mall Hotel & Convention Center

Wyndham Panama Albrook Mall Hotel & Convention Center

4.0 out of 5.0 Ave. Marginal Avenida Ancon 1451, Santa Ana, Panama City, Panama
4.1/5
(9 Reviews)
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour fitness center. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Unwind with a drink at one of the 2 bars/lounges and enjoy the free buffet breakfast.
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Crowne Plaza Panama Airport

Crowne Plaza Panama Airport

4.0 out of 5.0 Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
4.1/5
(17 Reviews)
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool, onsite laundry facilities, and supervised childcare. Enjoy the 24-hour fitness center and perks like free self parking and a free airport shuttle.
$116
Sheraton Grand Panama

Sheraton Grand Panama

4.5 out of 5.0 Via Israel And 77th Street, Panama City, Panama
4/5
(13 Reviews)
This smoke-free resort features a casino, a full-service spa, and 3 restaurants. Families will appreciate the playground, kid-friendly dining, and in-room childcare. Enjoy the 3 outdoor tennis courts and perks like free valet parking and free WiFi.
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Dreams Playa Bonita Panama - Optional All Inclusive

Dreams Playa Bonita Panama - Optional All Inclusive

4.0 out of 5.0 KM 7, Road to Veracruz, Panama City, Panama
3.9/5
(7 Reviews)
This smoke-free resort features a full-service spa, a nightclub, and 6 restaurants. Spend a day at the beach kayaking, or relax with free beach cabanas and sun loungers. There's fun for all ages with a free kid's club and a children's pool, and in-room childcare is an added bonus.
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Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4.0 out of 5.0 Vía Tocumen, Entrance to Corredor Sur, Tocumen, Panama
3.6/5
(60 Reviews)
A casino, 2 restaurants, and 2 indoor tennis courts are all featured at this smoke-free resort. Bring the family and enjoy the children's pool, playground, and kid-friendly dining. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and valet parking.
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4 Star Hotels San Francisco

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in San Francisco 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in San Francisco will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in San Francisco, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent San Francisco Hotel Reviews By Fellow Wanderers

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.