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Due to coronavirus (COVID-19) travel advisories, some destinations may be unavailable for certain dates. Find out more.

All the big car rental brands = easy price comparison

Book your flight + hotel + car together to get the biggest discount

Free cancellation on most car rentals, and you can book now and pay later!

Top Car Rental Deals in Mayo Clinic

See all Mayo Clinic car rentals

Most Frequently Booked Mayo Clinic Hotels

$119
Kahler Grand Hotel

Kahler Grand Hotel

3.0 out of 5.0 20 2nd Ave Sw, Rochester, MN
3.6/5
(31 Reviews)
This smoke-free hotel includes 3 restaurants, an indoor pool, and a 24-hour fitness center. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. You'll appreciate the sauna, bar/lounge, and coffee shop.
$98
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5.0 9 3rd Ave Nw, Rochester, MN
3.5/5
(33 Reviews)
This hotel features a restaurant, a fitness center, and a bar/lounge. WiFi in public areas is free. You'll appreciate the area shuttle, self parking, and business center.
$106
Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area

2.5 out of 5.0 831 16th Street SW, Rochester, MN
4.8/5
(5 Reviews)
This hotel features an indoor pool and a fitness center. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free perks include daily breakfast, free self parking, and an area shuttle.

Mayo Clinic car rentals

On your next trip to Mayo Clinic, don’t build your exploring around public transportation schedules. Instead, rent a car in Mayo Clinic and venture out whenever and wherever you like.

Benefits of renting a car
Whether you’re visiting for business or leisure, picking up a cheap rental car in Mayo Clinic will help you see things at your own pace. Visit various attractions and go sightseeing at will instead of forking out money on rideshares or figuring out which bus or train connections you’ll need to make. You can even go on a road trip and see what the area around Mayo Clinic has to offer.

Jazz up your getaway
Car rental companies make it easy to pick out the perfect set of wheels for your trip. Need to impress some company higher-ups? Request a luxury vehicle with leather seats and surround sound. Want to cart the entire family around? An SUV or minivan will hold everyone in safety and comfort. Traveling by yourself or with your sweetheart? Pull out all the stops with a sports car and step on the gas. We can almost feel the wind in your hair!

Comfort and convenience
Book a rental car from Mayo Clinic Airport and start your adventure as soon as you land. There’s no need to scour car rental company websites to find your best ride. Instead, rent a car in Mayo Clinic from Travelocity and save money while you do.

How Much Does it Cost to Rent a Car in Mayo Clinic?

The cheapest car rentals in Mayo Clinic found within the past 7 days were $32 per day. Prices and availability subject to change. Additional terms may apply.