Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Tonight Feb 26 - Feb 27
This weekend Feb 28 - Mar 1
Next weekend Mar 6 - Mar 8

Best Luxury Hotels in Lake Nona Medical City

$167
Courtyard Orlando Lake Nona

Courtyard Orlando Lake Nona

3.0 out of 5.0 6955 Lake Nona Boulevard, Orlando, FL
4.5/5
(4 Reviews)
This hotel features an outdoor pool, a fitness center, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Unwind with a drink at the bar/lounge and enjoy perks like free self parking and a free area shuttle.

5 Star Hotels in Lake Nona Medical City

$810
Four Seasons Resort Orlando at WALT DISNEY WORLD® Resort

Four Seasons Resort Orlando at WALT DISNEY WORLD® Resort

5.0 out of 5.0 10100 Dream Tree Blvd., Lake Buena Vista, FL
5/5
(8 Reviews)
Located on a lake, this family-friendly resort is within 6 mi (10 km) of Disney's Lake Buena Vista Golf Course, Epcot®, and Disney's Typhoon Lagoon Water Park. Disney's Hollywood Studios® and Disney Springs® are also within 6 mi (10 km).
$151
Reunion Resort & Golf Club

Reunion Resort & Golf Club

5.0 out of 5.0 7593 Gathering Drive, Kissimmee, FL
4.6/5
(63 Reviews)
Located in the suburbs, this family-friendly resort is within 12 mi (20 km) of Disney's Animal Kingdom® Theme Park, ESPN Wide World of Sports, and Epcot®. Disney's Hollywood Studios® and Orlando Vineland Premium Outlets are also within 16 mi (25 km).
$459
Waldorf Astoria Orlando

Waldorf Astoria Orlando

5.0 out of 5.0 14200 Bonnet Creek Resort Lane, Orlando, FL
4.2/5
(23 Reviews)
Set in Orlando, this family-friendly resort is within 6 mi (10 km) of Disney's Hollywood Studios®, ESPN Wide World of Sports, and Epcot®. Disney's Animal Kingdom® Theme Park and Discovery Cove are also within 9 mi (15 km).

4 Star Hotels in Lake Nona Medical City

$199
Hyatt Regency Orlando International Airport

Hyatt Regency Orlando International Airport

4.0 out of 5.0 9300 Jeff Fuqua Boulevard, Orlando, FL
4.6/5
(102 Reviews)
Located in Southeast Orlando, this hotel is within 12 mi (20 km) of Florida Mall, Amway Center, and Orange County Convention Center. Aquatica and Gatorland® are also within 16 mi (25 km).
$179
Walt Disney World Dolphin

Walt Disney World Dolphin

4.0 out of 5.0 1500 Epcot Resort Blvd, Lake Buena Vista, FL
4/5
(454 Reviews)
Nestled on the beach, this Bay Lake resort is within 1 mi (2 km) of Disney's Fantasia Gardens Miniature Golf Course, Disney's Hollywood Studios®, and Disney's Boardwalk. Epcot® and Disney's Blizzard Beach Water Park are also within 2 mi (3 km).
$99
Sheraton Orlando Lake Buena Vista Resort

Sheraton Orlando Lake Buena Vista Resort

4.0 out of 5.0 12205 S Apopka Vineland Rd, Orlando, FL
3.7/5
(78 Reviews)
This family-friendly Orlando resort is within 3 mi (5 km) of Disney Springs®, Orlando Vineland Premium Outlets, and Disney's Lake Buena Vista Golf Course. SeaWorld® Orlando and Orange County Convention Center are also within 6 mi (10 km).

Travelers Like You Recently Booked These Lake Nona Medical City Hotels

Map

Lake Nona Medical City Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Lake Nona Medical City luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Lake Nona Medical City to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Lake Nona Medical City will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Lake Nona Medical City, and plan your next opulent escape.


Recent Lake Nona Medical City Hotel Reviews By Fellow Wanderers

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.