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Hotels near Main Street Cultural District

Comfort Inn and Suites Ames near ISU Campus

Comfort Inn and Suites Ames near ISU Campus

2.5 out of 5
603 South 16th Street, Ames, IA
Free Cancellation
Reserve now, pay when you stay
1.13 mi from Main Street Cultural District
The price is $88 per night
$88
per night
Apr 24 - Apr 25
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like full breakfast and free self parking.
GrandStay Hotel & Suites

GrandStay Hotel & Suites

2.5 out of 5
1606 S Kellogg Ave, Ames, IA
Free Cancellation
Reserve now, pay when you stay
1.22 mi from Main Street Cultural District
The price is $76 per night
$76
per night
Apr 22 - Apr 23
This hotel features an indoor pool, a spa tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like on-the-go breakfast and free self parking.
Hot Tub
Pet friendly
SpringHill Suites by Marriott Ames

SpringHill Suites by Marriott Ames

2.5 out of 5
1810 SE 16TH STREET, Ames, IA
Free Cancellation
Reserve now, pay when you stay
1.78 mi from Main Street Cultural District
The price is $93 per night
$93
per night
May 5 - May 6
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the laundry service. Enjoy the indoor pool and conveniences like a 24-hour front desk and laundry facilities.
Iowa House

Iowa House

3 out of 5
405 Hayward Ave., Ames, IA
1.92 mi from Main Street Cultural District
The price is $135 per night
$135
per night
May 5 - May 6
This bed & breakfast features free WiFi in public areas, free newspapers, and free self parking. Free full breakfast is served. A business center, a snack bar/deli, and a lobby fireplace are also on offer.
Hampton Inn & Suites Ames

Hampton Inn & Suites Ames

2.5 out of 5
2100 Southeast 16th Street, Ames, IA
Free Cancellation
Reserve now, pay when you stay
1.96 mi from Main Street Cultural District
The price is $107 per night
$107
per night
Apr 21 - Apr 22
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free breakfast, free WiFi, and free self parking. A business center, dry cleaning, and luggage storage are also on offer.
Fairfield Inn & Suites by Marriott Ames

Fairfield Inn & Suites by Marriott Ames

2.5 out of 5
2137 Isaac Newton Drive, Ames, IA
Free Cancellation
Reserve now, pay when you stay
1.97 mi from Main Street Cultural District
The price is $72 per night
$72
per night
Apr 24 - Apr 25
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like full breakfast and free self parking.
Microtel Inn & Suites by Wyndham Ames

Microtel Inn & Suites by Wyndham Ames

2 out of 5
2216 Se 16th St, Ames, IA
Free Cancellation
Reserve now, pay when you stay
2.04 mi from Main Street Cultural District
The price is $65 per night
$65
per night
May 1 - May 2
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour business center. Enjoy the 24-hour gym and conveniences like a 24-hour front desk and laundry facilities.
Best Western Plus University Park Inn & Suites

Best Western Plus University Park Inn & Suites

2.5 out of 5
2500 University Blvd., Ames, IA
Free Cancellation
Reserve now, pay when you stay
2.05 mi from Main Street Cultural District
The price is $80 per night
$80
per night
May 5 - May 6
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the spa tub and free perks like continental breakfast and free self parking.
Hot Tub
Pet friendly
Gateway Hotel and Conference Center at Iowa State University

Gateway Hotel and Conference Center at Iowa State University

3 out of 5
2100 Green Hills Drive, Ames, IA
Free Cancellation
Reserve now, pay when you stay
2.1 mi from Main Street Cultural District
The price is $99 per night
$99
per night
May 5 - May 6
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference space. Enjoy the gym and perks like free self parking.
Country Inn & Suites by Radisson, Ames, IA

Country Inn & Suites by Radisson, Ames, IA

2.5 out of 5
2605 Se 16th St, Ames, IA
Free Cancellation
2.15 mi from Main Street Cultural District
The price is $94 per night
$94
per night
May 5 - May 6
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the spa tub and free perks like continental breakfast and free self parking.
AmericInn by Wyndham Ames

AmericInn by Wyndham Ames

2.5 out of 5
2507 SE 16th St., Ames, IA
Free Cancellation
Reserve now, pay when you stay
2.17 mi from Main Street Cultural District
The price is $75 per night
$75
per night
Apr 21 - Apr 22
This hotel features an indoor pool and a spa tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Hot Tub
Pet friendly
Radisson Hotel Ames Conference Center at ISU

Radisson Hotel Ames Conference Center at ISU

3 out of 5
2609 University Blvd, Ames, IA
Free Cancellation
2.19 mi from Main Street Cultural District
The price is $71 per night
$71
per night
Apr 21 - Apr 22
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Relax with a drink at the bar/lounge and enjoy perks like free self parking.
Pet friendly
Breakfast available
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Hotels Close to Main Street Cultural District

Your next vacation is around the corner. The kids are out of school, you and the spouse have two weeks off, and it’s about time to get the heck out of dodge. You must experience the culture and see the sights. Book your stay Main Street Cultural District hotels with us at Travelocity and enjoy the trip of a lifetime.

Finally, you can stay near the sites you’ve only read about in books. Now they are next door. Start fresh in the morning with the amazing views from your balcony. Then hop on any number of tour buses and take postcard-worthy pictures of the attractions you once thought couldn’t be real, but now you find them through your lens. Hotels near Main Street Cultural District will offer you the best in prices, activities, amenities, dining, and nightlife.

You may not want to imitate the Griswald’s--that’s been done one too many times—but you do want to have a memorable trip. With Travelocity’s long list of cheap hotels near Main Street Cultural District, you’re sure to find the perfect place to stay within your preferred budget. We’ll match a lower price and refund the difference. Book now and let us make your next vacation the easiest of your life.

Main Street Cultural District hotels essential information

Accommodation
664 hotels
Lowest Price
$65
Highest Price
$135
Popular hotels
Gateway Hotel and Conference Center at Iowa State University, AmericInn by Wyndham Ames, Best Western Plus University Park Inn & Suites, GrandStay Hotel & Suites, Comfort Inn and Suites Ames near ISU Campus, Radisson Hotel Ames Conference Center at ISU, Country Inn & Suites by Radisson, Ames, IA, SpringHill Suites by Marriott Ames, Microtel Inn & Suites by Wyndham Ames, Fairfield Inn & Suites by Marriott Ames, Hampton Inn & Suites Ames, Iowa House

Recent Main Street Cultural District hotel reviews by fellow wanderers

AmericInn by Wyndham Ames

AmericInn by Wyndham Ames

5 out of 5
Posted 19 hours ago
Travelocity Verified Review
"We have stayed here multiple times. Each time has been excellent. "
A verified traveler stayed at AmericInn by Wyndham Ames
AmericInn by Wyndham Ames

Types of hotels

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Areas of Main Street Cultural District