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Tonight Feb 23 - Feb 24
This weekend Feb 28 - Mar 1
Next weekend Mar 6 - Mar 8

Hotels near Mayo Clinic

Price for 1 night 2 adults*

$370

Mar 9 - Mar 10

Per night/room

The Towers At Kahler Grand Hotel

The Towers At Kahler Grand Hotel

4.0 out of 5.0 20 2nd Ave SW, Rochester, MN
4/5
(2 Reviews)
96 m from Mayo Clinic
This smoke-free hotel includes 2 restaurants, an indoor pool, and a fitness center. Traveling on business? Take advantage of the 14 conference rooms, business center, and free valet parking. Relax with a drink at the bar/lounge and enjoy free perks like English breakfast and free self parking.
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$101

Feb 29 - Mar 1

Per night/room

Kahler Grand Hotel

Kahler Grand Hotel

3.0 out of 5.0 20 2nd Ave Sw, Rochester, MN
3.3/5
(73 Reviews)
0.1 km from Mayo Clinic
This smoke-free hotel includes 3 restaurants, an indoor pool, and a 24-hour fitness center. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. You'll appreciate the sauna, bar/lounge, and coffee shop.
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$169

Mar 6 - Mar 7

Per night/room

Marriott Rochester Mayo Clinic

Marriott Rochester Mayo Clinic

3.5 out of 5.0 101 1st Ave Sw, Rochester, MN
4.7/5
(7 Reviews)
0.2 km from Mayo Clinic
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and airport shuttle. Enjoy the 24-hour fitness center and perks like a free shopping center shuttle.
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$112

Mar 14 - Mar 15

Per night/room

Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5.0 9 3rd Ave Nw, Rochester, MN
3.6/5
(55 Reviews)
0.2 km from Mayo Clinic
This hotel features an indoor pool, a fitness center, and a restaurant. Unwind with a drink at the bar/lounge and enjoy perks like free continental breakfast and free WiFi. You'll appreciate the area shuttle, self parking, and business center.
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$148

Mar 5 - Mar 6

Per night/room

DoubleTree by Hilton Hotel Rochester - Mayo Clinic Area

DoubleTree by Hilton Hotel Rochester - Mayo Clinic Area

3.5 out of 5.0 150 S Broadway, Rochester, MN
4.5/5
(13 Reviews)
0.3 km from Mayo Clinic
This hotel features an indoor pool, a 24-hour fitness center, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy the sauna and perks like a free area shuttle.
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$129

Feb 29 - Mar 1

Per night/room

Residence Inn by Marriott Rochester Mayo Clinic Area

Residence Inn by Marriott Rochester Mayo Clinic Area

3.0 out of 5.0 441 W Center St Nw, Rochester, MN
3/5
(2 Reviews)
0.3 km from Mayo Clinic
This hotel features a fitness center and a rooftop terrace. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free full breakfast is served.
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$143

Mar 1 - Mar 2

Per night/room

Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

3.0 out of 5.0 225 S Broadway, Rochester, MN
4.4/5
(14 Reviews)
0.3 km from Mayo Clinic
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy the 24-hour fitness center and perks like a free area shuttle.
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$179

Mar 1 - Mar 2

Per night/room

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

3.5 out of 5.0 10 East Center Street, Rochester, MN
5/5
(4 Reviews)
0.4 km from Mayo Clinic
A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a 24-hour fitness center on site, and a 24-hour front desk and a fireplace in the lobby are also provided.
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$107

Mar 1 - Mar 2

Per night/room

Holiday Inn Rochester Downtown

Holiday Inn Rochester Downtown

3.0 out of 5.0 220 S Broadway, Rochester, MN
0.4 km from Mayo Clinic
This hotel features a restaurant, a 24-hour fitness center, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Self parking, express check-in, and express check-out are also offered.
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$125

Feb 27 - Feb 28

Per night/room

Brentwood Inn & Suites

Brentwood Inn & Suites

2.5 out of 5.0 123 Fourth Ave. NW, Rochester, MN
3.8/5
(12 Reviews)
0.4 km from Mayo Clinic
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour business center. Laundry facilities and free newspapers are also provided.
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$68

Feb 28 - Feb 29

Per night/room

5th Avenue Inn and Suites

5th Avenue Inn and Suites

2.0 out of 5.0 20 5th Ave NW, Rochester, MN
4.2/5
(12 Reviews)
0.5 km from Mayo Clinic
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free self parking, and a free area shuttle. Business travelers can take advantage of the free WiFi in public areas. A lobby fireplace, a computer station, and luggage storage are also on offer.
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$100

Feb 24 - Feb 25

Per night/room

Centerstone Plaza Hotel Soldiers Field/Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field/Mayo Clinic Area

3.0 out of 5.0 401 6th St Sw, Rochester, MN
3.7/5
(16 Reviews)
0.7 km from Mayo Clinic
This hotel features an indoor pool, a 24-hour fitness center, and a restaurant. There's fun for all ages with a children's pool and an arcade/game room, and families will appreciate the onsite laundry facilities. Enjoy the spa tub and free perks like buffet breakfast and free self parking.
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See all 181 Properties near Mayo Clinic
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How much is a hotel room in Mayo Clinic?

Hotels in Mayo Clinic start at $68 per night. Prices and availability subject to change. Additional terms may apply.

Mayo Clinic Hotel & Travel Guide

You're bound to enjoy your visit to Mayo Clinic.

It is located in Rochester, roughly 70 miles (113 kilometers) from the state capital, St. Paul.

Finding a great accommodation is a crucial component of any good trip. If you want to set up camp near Mayo Clinic, you'll be able to find around 30 options to select from. 0.07 miles (0.11 kilometers) away, you'll find the Marriott Rochester Mayo Clinic. A couple of other places to check out are the Residence Inn by Marriott Rochester Mayo Clinic Area, 0.2 miles (0.3 kilometers) away, and the DoubleTree by Hilton Hotel Rochester - Mayo Clinic Area, 0.2 miles (0.3 kilometers) away.

The less cash you spend, the longer your vacation can last! There are some great bargains on hotels here. Some examples are the Days Inn Rochester and the Super 8 Rochester/Fairgrounds Area, which are 0.10 miles (0.16 kilometers) and 1 mile (2 kilometers) away, respectively.

If you'd like a short rest from wandering around Mayo Clinic, take the short walk to Jazzman's Cafe for a strong coffee. Or, perhaps you might sample a full meal at Patient / Visitor Cafeteria (Mayo), also nearby. If you have no plans to go home just yet, have a refreshing glass of your favorite wine or beer at Grand Grill, also just down the road.

Other Things to Do Near Mayo Clinic

If you have time, you'll want to discover what else is happening in the area:

  • See what on-campus lifestyle is like in another area when you visit University of Minnesota-Rochester. Make sure you arrange to come when the college is open to the public.
  • Shops University Square is a leading shopping destination, boasting an impressive selection of stores and eating options.
  • Attend a performance and admire a few of the exhibits that are featured at Rochester Art Center.
  • Enjoy a play and temporarily escape to a different world at Rochester Civic Theater.
  • If you're seeking a truly moving experience, join the locals at Soldiers Field Veterans Memorial.

Recent Mayo Clinic Hotel Reviews By Fellow Wanderers

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

4.0 Travelocity Verified Review
Close to St Mary's. The parking garage is an ADDITIONAL charge of $11.00/day.
1 week ago by A verified traveler from Charlevoix
Open Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys hotel guest reviews

Kahler Grand Hotel

4.0 Travelocity Verified Review
Very convenient. Staff is lovely. Construction is a pain.
1 week ago by A verified traveler from Seattle
Open Kahler Grand Hotel hotel guest reviews

Marriott Rochester Mayo Clinic

5.0 Travelocity Verified Review
I like that it’s connected to Mayo and all the shops I could get to inside.
4 weeks ago by A verified traveler
Open Marriott Rochester Mayo Clinic hotel guest reviews

5th Avenue Inn and Suites

5.0 Travelocity Verified Review
This was a reasonably priced hotel for a stay while having tests at Mayo Clinic. Room was a nice size, sitting area, microwave, sink and refrigerator area too. Could use some updates, but all was clean.The morning breakfast area was great. Plenty of fresh fruit and breakfast items. The front desk staff was helpful and always a greeting upon entry. Cookies at desk late afternoon was a nice treat.
1 month ago by A verified traveler
Open 5th Avenue Inn and Suites hotel guest reviews

Brentwood Inn & Suites

4.0 Travelocity Verified Review
It was clean, pleasant and easy to get to. Good shopping and not very far to the shopping center
2 months ago by A verified traveler
Open Brentwood Inn & Suites hotel guest reviews

DoubleTree by Hilton Hotel Rochester - Mayo Clinic Area

5.0 Travelocity Verified Review
Didnt like the mold behind the curtains in room 809 corner of the wall and windowsill. Other than that it was great 👍
2 months ago by A verified traveler
Open DoubleTree by Hilton Hotel Rochester - Mayo Clinic Area hotel guest reviews

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.