We rented this home for an adults only trip to the Keys. It was a mix of related and not related couples, but we had a blast and everyone had space. The second room only having access through the master worked for us since we had related people on the trip, but it was a minor inconvenience and we knew about it when we booked. If you had young kids with you, it would probably be a great fit.
We brought bikes and had fun exploring Summerland.
The tiki bar (Tonio's) is walking distance and a great little hangout. There are lots of other places 5-10 min drive.
Key West is about 30 mins and Ubers are expensive, so just plan on that if you're going to party there.
Owner was supportive and great to communicate with.
We would definitely stay here again for adults only or with kids.