Southern Illinois Vacation Packages

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Flight and hotel packages to Southern Illinois

Price found within the past 48 hours. Click for updated prices.
River City Casino & Hotel

River City Casino & Hotel

4 out of 5
per person
Jul 17 - Jul 22
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
This hotel features a casino, a nightclub, and 5 restaurants. Traveling on business? Take advantage of the business center, conference center, and conference space. Enjoy the 24-hour gym and perks like free self parking.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Save 100% on your flight
per person
Jul 17 - Jul 22
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the spa tub and free perks like continental breakfast and free self parking.
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
Save 100% on your flight
per person
Jul 17 - Jul 22
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
This luxury hotel features a casino, a full-service spa, and 5 restaurants. Enjoy the 2 spa tubs and 24-hour gym, and unwind with a drink at the poolside bar.
The Charles F. Knight Center

The Charles F. Knight Center

2.5 out of 5
Save 100% on your flight
per person
Jul 17 - Jul 22
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
This hotel features 3 restaurants and a bar/lounge. WiFi in public areas is free. Self parking and a coffee shop are also offered on site.
Hilton St. Louis Airport

Hilton St. Louis Airport

3.5 out of 5
Woodson Terrace
per person
Jul 17 - Jul 22
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, express check-in, and free airport shuttle. A free area shuttle is offered as well.

Top Southern Illinois hotel deals

Drury Inn & Suites Mt. Vernon

Drury Inn & Suites Mt. Vernon

3 out of 5
145 North 44th Street , Mount Vernon, IL
Free Cancellation
Reserve now, pay when you stay
The price is $112 per night
$112
per night
May 30 - May 31
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the 24-hour gym and free perks like buffet breakfast and free self parking.
Hot Tub
Pet friendly
Walker's Bluff Casino Resort

Walker's Bluff Casino Resort

4.5 out of 5
777 Walkers Bluff Way, Carterville, IL
Free Cancellation
Reserve now, pay when you stay
The price is $150 per night
$150
per night
Jun 12 - Jun 13
This luxury resort features a casino, a full-service spa, and 3 restaurants. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy perks like free self parking.
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

3 out of 5
1118 Central Park Drive, O'Fallon, IL
Free Cancellation
Reserve now, pay when you stay
The price is $108 per night
$108
per night
May 28 - May 29
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Hot Tub
Pet friendly
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

3 out of 5
12 Ludwig Dr, Fairview Heights, IL
Free Cancellation
Reserve now, pay when you stay
The price is $99 per night
$99
per night
May 28 - May 29
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Hot Tub
Pet friendly
DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon

4 out of 5
222 Potomac Blvd, Mount Vernon, IL
Free Cancellation
Reserve now, pay when you stay
The price is $105 per night
$105
per night
Jun 23 - Jun 24
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like free self parking and free WiFi. A business center, a terrace, and express check-in are also on offer.
Breakfast available
Pool
Country Inn & Suites by Radisson, Fairview Heights, IL

Country Inn & Suites by Radisson, Fairview Heights, IL

3 out of 5
140 Ludwig Drive, Fairview Heights, IL
Free Cancellation
The price is $70 per night
$70
per night
May 28 - May 29
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit in Southern Illinois

Image for St. Louis Union Station

St. Louis Union Station

4/5(615 reviews)

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.

St. Louis Union Station
Image for Gateway Arch

Gateway Arch

4.5/5(2,511 reviews)

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch
Image for St. Louis Zoo

St. Louis Zoo

4.5/5(1,212 reviews)

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

St. Louis Zoo

Frequently asked questions

How much are vacation packages to Southern Illinois?
Vacation packages, including flights and hotels in Southern Illinois, are priced from as little as $479. Make your travel dreams come true and book your dream trip with Travelocity today.
Where can I get the best vacation package deals for Southern Illinois?
Travelocity has countless ways to score an incredible Southern Illinois package deal. Select from 400 airlines and 1,000,000 properties around the globe and put together a vacation package that’s right for you. With this amount of choice at your fingertips, you’ll have plenty of inspiration for your next big escape.
Why should I purchase my Southern Illinois vacation bundle with Travelocity?
Because life is all about the journey, and we have everything you need to get you on your way. With our top-notch service and Price Match Guarantee, you can organize your trip with confidence. Plus, you can sleep easy while you’re away knowing we’re always available to chat via our 24/7 customer support.
Will I save money on my Southern Illinois car rental if I bundle it with a hotel or flight?
Definitely. And our Southern Illinois vacation packages are the best way to do it. In only a few clicks you can save money as well as time by bundling your bookings. Collect the keys to your rental car then set your own course. Searching for things to do? Add some activities or experiences to your package and make savings on those too.
What is the best time of year to go to Southern Illinois?
If you’re all about wandering wisely, is one of the best times to do it. That’s when room rates are at their lowest. By way of comparison, prices surge in . June, July and August are the most popular months to visit Southern Illinois, so expect long lines for top attractions. Hoping to avoid the busy season? You’ll find fewer visitors in December, January and February.
Which airport is best for Southern Illinois?
Working out where you disembark your plane in Southern Illinois is a piece of cake — most airlines fly in and out of Williamson County Regional Airport (MWA).