Deals on vacations and trips to Southwest Illinois

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Southwest Illinois flight + hotel vacation packages

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River City Casino & Hotel

River City Casino & Hotel

4 out of 5
per person
Jul 17 - Jul 22
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
This hotel features a casino, a nightclub, and 5 restaurants. Traveling on business? Take advantage of the business center, conference center, and conference space. Enjoy the 24-hour gym and perks like free self parking.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Save 100% on your flight
per person
Jul 17 - Jul 22
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the spa tub and free perks like continental breakfast and free self parking.
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
Save 100% on your flight
per person
Jul 17 - Jul 22
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
This luxury hotel features a casino, a full-service spa, and 5 restaurants. Enjoy the 2 spa tubs and 24-hour gym, and unwind with a drink at the poolside bar.
The Charles F. Knight Center

The Charles F. Knight Center

2.5 out of 5
Save 100% on your flight
per person
Jul 17 - Jul 22
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
This hotel features 3 restaurants and a bar/lounge. WiFi in public areas is free. Self parking and a coffee shop are also offered on site.
Hilton St. Louis Airport

Hilton St. Louis Airport

3.5 out of 5
Woodson Terrace
per person
Jul 17 - Jul 22
found 1 day ago
Roundtrip flight included
Denver (DEN) to St. Louis (STL)
This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, express check-in, and free airport shuttle. A free area shuttle is offered as well.

Top Southwest Illinois hotel deals

Drury Inn & Suites Mt. Vernon

Drury Inn & Suites Mt. Vernon

3 out of 5
145 North 44th Street , Mount Vernon, IL
Free Cancellation
Reserve now, pay when you stay
The price is $112 per night
$112
per night
May 30 - May 31
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the 24-hour gym and free perks like buffet breakfast and free self parking.
Hot Tub
Pet friendly
Walker's Bluff Casino Resort

Walker's Bluff Casino Resort

4.5 out of 5
777 Walkers Bluff Way, Carterville, IL
Free Cancellation
Reserve now, pay when you stay
The price is $150 per night
$150
per night
Jun 12 - Jun 13
This luxury resort features a casino, a full-service spa, and 3 restaurants. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy perks like free self parking.
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

3 out of 5
1118 Central Park Drive, O'Fallon, IL
Free Cancellation
Reserve now, pay when you stay
The price is $108 per night
$108
per night
May 28 - May 29
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

3 out of 5
12 Ludwig Dr, Fairview Heights, IL
Free Cancellation
Reserve now, pay when you stay
The price is $99 per night
$99
per night
May 28 - May 29
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Hot Tub
Pet friendly
DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon

4 out of 5
222 Potomac Blvd, Mount Vernon, IL
Free Cancellation
Reserve now, pay when you stay
The price is $105 per night
$105
per night
Jun 23 - Jun 24
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like free self parking and free WiFi. A business center, a terrace, and express check-in are also on offer.
Country Inn & Suites by Radisson, Fairview Heights, IL

Country Inn & Suites by Radisson, Fairview Heights, IL

3 out of 5
140 Ludwig Drive, Fairview Heights, IL
Free Cancellation
The price is $70 per night
$70
per night
May 28 - May 29
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Image for St. Louis Union Station

St. Louis Union Station

4/5(615 reviews)

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.

St. Louis Union Station
Image for Gateway Arch

Gateway Arch

4.5/5(2,511 reviews)

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch
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St. Louis Zoo

4.5/5(1,212 reviews)

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

St. Louis Zoo

Frequently asked questions

How much are vacation packages to Southwest Illinois?
You might be surprised — you could find yourself in Southwest Illinois for as little as $479. At Travelocity, we save you time and money with our awesome vacation packages. With flights, hotels and tours all ready to go, why put it off?
Where can I get the best vacation package deals for Southwest Illinois?
Your dream vacation can be booked through Travelocity. With access to 400 airlines and at least 1,000,000 hotels all over the world, selecting the perfect Southwest Illinois package deal couldn’t be simpler.
Why should I book my Southwest Illinois vacation package with Travelocity?
From incredible destinations to thrilling experiences, we have everything you need to satisfy your love for travel. Our 24/7 customer care will also ensure you’re taken care of before, during and after your trip. And don’t fret if you spot a cheaper price on your reservation, we’ll match it. That’s our Price Match Guarantee.
Can I save on my Southwest Illinois car rental if I bundle it with hotels and flights?
Combining your bookings into a Southwest Illinois vacation package will certainly save you money. You can book a car and flight; a hotel, flight and car; or a car and hotel. You won’t find a better way to explore the greater Southwest Illinois area than with your own rental car. You can also add experiences and tours to your Travelocity package.
What is the best time of year to go to Southwest Illinois?
You’ll score the cheapest hotel prices in and pay more during . It’s generally less busy in December, January and February, while there’ll be more fellow visitors to hang out with during June, July and August. It all comes down to how much you’re willing to spend, the weather and how you handle crowds.
Which airport is best for Southwest Illinois?
Lambert-St. Louis Intl. Airport (STL) and Williamson County Regional Airport (MWA) are your best options for flying to Southwest Illinois.