$128 Cheap American Airlines flights from Des Moines to Key West (DSM to EYW)

Find The Best Day To Fly from Des Moines to Key West

Amazing American Airlines DSM to EYW Flight Deals

The cheapest flights to Key West Intl. found within the past 7 days were $272 round trip and $128 one way. Prices and availability subject to change. Additional terms may apply.

EYW From DSM Economy Coach Packages on Similar Airlines

Price found within the past 48 hours. Click for updated prices.
Oceans Edge Key West Resort, Hotel & Marina
Beachside Resort & Residences
Don't see what you're looking for?
See all available trips from Des Moines Intl. to Key West Intl.
View all trips

Frequently asked questions

Can I catch a flight from DSM to Key West Intl. Airport right now?
For information on any present Key West Intl. Airport quarantine requirements and travel advice, visit our Covid-19 Travel Advisor. Look before you arrange your flight, so you don’t get caught up en route.
What terminal is American Airlines at Des Moines Intl. Airport (DSM)?
Once you’re issued with the boarding pass for your American Airlines flight from DSM to Key West Intl. Airport, you should be able to determine which terminals you’ll be flying in and out of. Your airline will be able to help if those details are missing from your ticket.
Are there American Airlines non-stop flights from DSM to EYW?
You won’t find any direct flights with American Airlines from DSM to EYW. You will have a stopover, so take the opportunity to go for a stroll and stretch out those legs before boarding your next flight.
How long is an American Airlines flight from DSM to EYW?
Bring that novel you’ve been longing to read. A flight from DSM to EYW with American Airlines takes roughly 4 hours and 45 minutes. You’ll have sufficient time to immerse yourself in the plot.
How many direct and indirect flights does American Airlines fly from DSM to EYW?
You’ll find there are around 2 American Airlines flights each day from DSM to EYW.
If I am not able to travel due to COVID-19, can I change my booking to a later date?
For more info about changing your flight to Key West Intl. Airport, please visit our Customer Service Portal.
What is the best day to buy a plane ticket?
This just in! Airfares offered on Thursdays tend to be the cheapest, according to flight demand on Travelocity in 2021. Tuesday and Wednesday prices are also good, but you may want to prepare your budget if booking during the weekend, as data shows that is when prices are generally at their highest.
What are the cheapest days to fly?
Frequent travelers may already know this, but earlier in the week can be the cheapest time to fly. In 2021, flights departing on a Monday were generally the cheapest of the week, whereas you may pay a premium for weekend flights when demand is usually high. On average, tickets were most expensive for Saturday departures, so if you need to fly out on a weekend, you might look for deals ahead of time.
How far in advance can you book a flight?
Trying to figure out how early you should book your flight? It’s possible to start comparing international airfares on Travelocity up to 12 months in advance. However, it does depend on the carrier as not all airlines release their prices that far out. According to our 2021 flight demand trends, last minute planners can still bag a bargain with some of the cheapest fares appearing 0-2 weeks prior to their travel dates.*According to flight demand on Travelocity.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Discover our best American Airlines flight from Des Moines DSM to Key West EYW 

To find the best deals on flights to Des Moines from Key West with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.  

 

Return flights from Des Moines DSM to Key West EYW with American Airlines 

If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $272 to $300, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply. 

 

Book one-way American Airlines flights from Des Moines DSM to Key West EYW 

A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Des Moines to Key West costs from $128. Prices and availability subject to change. Additional terms may apply. 

 

The easy way to find cheap flights to Key West EYW from  Des Moines DSM with American Airlines 

To find a cheap American Airlines flight from Des Moines DSM to Key West EYW, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference. 

 

How to find our best airfare deals on American Airlines flights from Des Moines DSM to Key West EYW 

If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as August, or if you book a flight with a stopover. 

 

Find nonstop flights from Des Moines DSM to Key West EYW with American Airlines 

If you’re keen to be on Key West soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it. 

 

Flexible airline tickets for American Airlines flights from Des Moines DSM to Key West EYW 

Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.  

 

There are a lot of reasons to book your flights to Key West EYW from  Des Moines DSM with American Airlines on Travelocity 

At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.

Travelers ❤️ these 🏨 after their flight to Key West

Hampton Inn Key West FL
Hampton Inn Key West FL
2.5 out of 5
3755 S Roosevelt Blvd, Key West, FL
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet ...
8.8/10 Excellent! (1,095 reviews)
"This is a mid size but clean and quiet. Breakfast is good and shuttle is convenient."

Reviewed on May 24, 2024

Hampton Inn Key West FL
Margaritaville Beach House Key West
Margaritaville Beach House Key West
4 out of 5
2001 South Roosevelt Boulevard, Key West, FL
This hotel features a restaurant, an outdoor pool, and a bar/lounge. If you want to take your pet along, this pet-friendly property offers everything you'll ...
8.4/10 Very Good! (1,766 reviews)
"Very convenient with all the amenities..... would recommend it to anyone"

Reviewed on May 27, 2024

Margaritaville Beach House Key West
DoubleTree Resort by Hilton Grand Key - Key West
DoubleTree Resort by Hilton Grand Key - Key West
4 out of 5
3990 S Roosevelt Blvd, Key West, FL
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
7.8/10 Good! (1,005 reviews)
"The shuttle that goes every hour and takes you to downtown near mallory square. Very good to have..thanks"

Reviewed on May 24, 2024

DoubleTree Resort by Hilton Grand Key - Key West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.