Northeast Missouri Vacation Packages

Save when you book Northeast Missouri package deals

Choose two or more items and save on your trip:

Flight and hotel packages to Northeast Missouri

Price found within the past 48 hours. Click for updated prices.
Bell's Extended Stay and Suites

Bell's Extended Stay and Suites

2 out of 5
per person
Aug 4 - Aug 10
found 1 day ago
Roundtrip flight included
Minneapolis (MSP) to St. Louis (STL)
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour business center. There's a gym on site, and a 24-hour front desk and a snack bar/deli are also provided.
River City Casino & Hotel

River City Casino & Hotel

4 out of 5
per person
Aug 9 - Aug 12
found 12 hours ago
Roundtrip flight included
New York (NYC) to St. Louis (STL)
This hotel features a casino, a nightclub, and 5 restaurants. Traveling on business? Take advantage of the business center, conference center, and conference space. Enjoy the 24-hour gym and perks like free self parking.
The Pennywell St.Louis Downtown, a Hilton Hotel

The Pennywell St.Louis Downtown, a Hilton Hotel

4 out of 5
Downtown St. Louis
per person
Aug 9 - Aug 12
found 12 hours ago
Roundtrip flight included
New York (NYC) to St. Louis (STL)
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the express check-in, express check-out, and valet parking. Self parking, dry cleaning, and luggage storage are also offered.
DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield

4 out of 5
per person
Jun 25 - Jun 30
found 1 hour ago
Roundtrip flight included
New York (NYC) to St. Louis (STL)
7 indoor tennis courts, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the seasonal outdoor pool and perks like free self parking.
The Westin St. Louis

The Westin St. Louis

4.5 out of 5
Downtown St. Louis
per person
Aug 9 - Aug 12
found 12 hours ago
Roundtrip flight included
New York (NYC) to St. Louis (STL)
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. Self parking, express check-out, and a computer station are also offered.

Top Northeast Missouri hotel deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
The price is $114 per night
$114
per night
Jun 9 - Jun 10
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the sauna and free full breakfast each morning.
Pet friendly
Breakfast included
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Free Cancellation
Reserve now, pay when you stay
The price is $130 per night
$130
per night
Jun 9 - Jun 10
A casino, 7 restaurants, and a 24-hour gym are all featured at this hotel. Traveling for business? Take advantage of the 24-hour business center, express check-out, and conference space. Relax with a drink at one of the 3 bars/lounges and enjoy perks like free self parking.
Breakfast available
Parking included
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
The price is $118 per night
$118
per night
Jun 14 - Jun 15
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. You'll appreciate the seasonal outdoor pool, bar/lounge, and laundry facilities.
Breakfast available
Pool
Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield

3 out of 5
15431 Conway Rd, Chesterfield, MO
Free Cancellation
Reserve now, pay when you stay
The price is $102 per night
$102
per night
May 30 - May 31
A full-service spa and a 24-hour gym are featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and free perks like continental breakfast and free self parking. A business center, free WiFi in public areas, and a garden are also on offer.
Pet friendly
Breakfast included
The Last Hotel

The Last Hotel

4.5 out of 5
1501 Washington Ave, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
The price is $137 per night
$137
per night
May 30 - May 31
This hotel features 2 bars/lounges, a poolside bar, and a restaurant. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. Enjoy the outdoor pool and conveniences like a 24-hour front desk and concierge services.
Pet friendly
Breakfast available
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
The price is $126 per night
$126
per night
May 30 - May 31
This hotel features an indoor pool, a gym, and a restaurant. Enjoy the steam room and perks like free WiFi. There's a bar/lounge on site, and a 24-hour front desk and concierge services are also provided.
Pet friendly
Breakfast available
Don't see what you're looking for?
See all available properties in Northeast Missouri
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit in Northeast Missouri

Image for St. Louis Union Station

St. Louis Union Station

4/5(615 reviews)

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.

St. Louis Union Station
Image for Gateway Arch

Gateway Arch

4.5/5(2,511 reviews)

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch
Image for St. Louis Zoo

St. Louis Zoo

4.5/5(1,212 reviews)

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

St. Louis Zoo

Photos of local treasures

St. Louis which includes interior views

Frequently asked questions

How much are vacation packages to Northeast Missouri?
Adventure awaits in Northeast Missouri, with Travelocity vacation packages starting as low as $414. Providing both flights and hotels, these incredible deals make it a cinch to experience more of our wonderful planet.
Where can I get the best vacation package deals for Northeast Missouri?
Landing an unbeatable package deal to Northeast Missouri is a breeze with Travelocity. With as many as 400 partner airlines and 1,000,000 properties across the globe, the choice is yours when selecting your hotels and flights.
Why should I book my Northeast Missouri vacation bundle via Travelocity?
Because we believe in creating one-of-a-kind travel experiences. From flights and hotels to car rentals and activities, everything is at your fingertips. Our customer support team is available 24/7 to ensure your needs are taken care of. We also offer a Price Match Guarantee, so you can secure your trip knowing you’ve landed the best deal possible. If you find a lower price, we’ll match it!
Will I save money on my Northeast Missouri car rental if I book it with hotels and flights?
Bundling your bookings into a Northeast Missouri vacation package will save you a handsome sum. Book a car and flight; a hotel, flight and car; or a hotel and car. You won’t find a better way to explore the greater Northeast Missouri region than from the driver’s seat of your own rental car. You can also add activities and experiences to your Travelocity package.
What is the best time of year to go to Northeast Missouri?
You’ll land the best hotel prices in and pay the most in . You can expect it to be quieter in January, October and December, while you’ll find more like-minded travelers to hang out with in March, May and June. It comes down to what prices you’re willing to pay, the weather conditions and how you handle crowds.
Which airport is best for Northeast Missouri?
Book an airfare to Quincy Regional-Baldwin Field Airport (UIN) or Kirksville Municipal Airport (IRK). They are the main options for people planning to visit Northeast Missouri.