Cheap Flights to Cape Girardeau from $69

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How Much Does it Cost To Fly To Cape Girardeau?

The cheapest prices found with in the last 7 days for return flights were $270 and $69 for one-way flights to Cape Girardeau for the period specified. Prices and availability are subject to change. Additional terms apply

OriginDestinationTravel DatesFlights From*
EWRScott CityApril 16 to April 18$354
MSYScott CityApril 15 to May 4$378
MSPScott CityApril 1 to April 7$406
STLScott CityMarch 25 to April 2$423
DCAScott CityMarch 24 to April 2$467
BWIScott CityMarch 24 to March 31$487
CMHScott CityMarch 27 to April 3$494
MCIScott CityMarch 31 to April 2$497
LAXScott CityApril 2 to April 7$574
SATScott CityMarch 26 to April 2$625
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
DCAScott CityMarch 23 to April 3$550
*Prices include taxes and fees

Cape Girardeau Flight Information

Traveling to
Cape Girardeau
Lowest Price
$270
Number of Airlines Serving
Airlines Serving
Contour Airlines, American Airlines
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Amazing Cape Girardeau Accommodation Deals

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
The price is $76 per night from Mar 24 to Mar 25
$76
includes taxes & fees
$67 per night
Mar 24 - Mar 25
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,004 reviews)
Wonderful stay
"We booked this very last minute and had a delightful stay. Clean, quiet rooms, with friendly staff. We will definitely use this franchise again."

Reviewed on Mar 14, 2025

Pear Tree Inn Cape Girardeau West
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 out of 5
3253 William Street, Cape Girardeau, MO
The price is $121 per night from Mar 23 to Mar 24
$121
includes taxes & fees
$107 per night
Mar 23 - Mar 24
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,003 reviews)
"Love everything"

Reviewed on Mar 10, 2025

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Quality Inn

Quality Inn

2.5 out of 5
2011 North Kingshighway, Cape Girardeau, MO
The price is $76 per night from Mar 18 to Mar 19
$76
includes taxes & fees
$67 per night
Mar 18 - Mar 19
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7/10 Good! (554 reviews)
"Property management very polite, the facility has all the amenities I need"

Reviewed on Feb 14, 2025

Quality Inn
Save an average of 15% on thousands of hotels when you're signed in
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St, Cape Girardeau, MO
The price is $76 per night from Mar 23 to Mar 24
$76
includes taxes & fees
$67 per night
Mar 23 - Mar 24
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,002 reviews)
"Very friendly staff and especially the ladies with breakfast with my grandsons who are 8 and 4"

Reviewed on Mar 14, 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Cape Girardeau

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Cape Girardeau
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, a water park, and patios. Popular attractions Riverfront Park and eDen Spa & Salon are located ...
9.8/10 Exceptional! (158 reviews)
Great stay
"Clean and large space. Easy access to lots of shops and restaurants. Great hosts."

Reviewed on Oct 26, 2024

Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St, Cape Girardeau, MO
The price is $76 per night from Mar 23 to Mar 24
$76
includes taxes & fees
$67 per night
Mar 23 - Mar 24
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,002 reviews)
"Very friendly staff and especially the ladies with breakfast with my grandsons who are 8 and 4"

Reviewed on Mar 14, 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
Quality Inn

Quality Inn

2.5 out of 5
2011 North Kingshighway, Cape Girardeau, MO
The price is $76 per night from Mar 18 to Mar 19
$76
includes taxes & fees
$67 per night
Mar 18 - Mar 19
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7/10 Good! (554 reviews)
"Property management very polite, the facility has all the amenities I need"

Reviewed on Feb 14, 2025

Quality Inn
Save an average of 15% on thousands of hotels when you're signed in
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive, Cape Girardeau, MO
The price is $107 per night from Mar 23 to Mar 24
$107
includes taxes & fees
$94 per night
Mar 23 - Mar 24
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (907 reviews)
"Staff was polite and very helpful and attentive. Will stay here the next time I’m passing through."

Reviewed on Mar 10, 2025

Drury Inn & Suites Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Cape Girardeau

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive, Cape Girardeau, MO
The price is $107 per night from Mar 23 to Mar 24
$107
includes taxes & fees
$94 per night
Mar 23 - Mar 24
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (907 reviews)
"Staff was polite and very helpful and attentive. Will stay here the next time I’m passing through."

Reviewed on Mar 10, 2025

Drury Inn & Suites Cape Girardeau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 out of 5
3253 William Street, Cape Girardeau, MO
The price is $121 per night from Mar 23 to Mar 24
$121
includes taxes & fees
$107 per night
Mar 23 - Mar 24
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,003 reviews)
"Love everything"

Reviewed on Mar 10, 2025

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St, Cape Girardeau, MO
The price is $76 per night from Mar 23 to Mar 24
$76
includes taxes & fees
$67 per night
Mar 23 - Mar 24
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,002 reviews)
"Very friendly staff and especially the ladies with breakfast with my grandsons who are 8 and 4"

Reviewed on Mar 14, 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
Save an average of 15% on thousands of hotels when you're signed in
Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Cape Girardeau
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, a water park, and patios. Popular attractions Riverfront Park and eDen Spa & Salon are located ...
9.8/10 Exceptional! (158 reviews)
Great stay
"Clean and large space. Easy access to lots of shops and restaurants. Great hosts."

Reviewed on Oct 26, 2024

Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Plane Tickets To Cape Girardeau

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Cape Girardeau. Browse through our inventory to explore a wide range of cheap flights to Cape Girardeau to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Cape Girardeau as you anxiously await to exit the plane and explore what Cape Girardeau has to offer. Considering all the amazing local food and culture in Cape Girardeau, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Cape Girardeau to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Cape Girardeau without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Cape Girardeau with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Cape Girardeau today!

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.