Book Hotels in Cape Girardeau, MO

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check hotel availability in Cape Girardeau

Tonight
Check prices in Cape Girardeau for tonight, Jun 23 - Jun 24
Tomorrow night
Check prices in Cape Girardeau for tomorrow night, Jun 24 - Jun 25
Next weekend
Check prices in Cape Girardeau for next weekend, Jun 28 - Jun 30

Top Cape Girardeau hotels