Create your free account
Sign in to your account
Wander Wisely with exceptional service, 24/7 support
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Most frequently booked Southeast Missouri hotels
Price for 1 night 2 adults*
Jan 26 - Jan 27
Per night/room
Drury Plaza Hotel Cape Girardeau Conference Center
Jan 26 - Jan 27
Per night/room
Pear Tree Inn Cape Girardeau West
Jan 26 - Jan 27
Per night/room
Auburn Place Hotel And Suites
Top cheap Southeast Missouri hotel deals
Price for 1 night 2 adults*
Jan 26 - Jan 27
Per night/room
Motel 6 Poplar Bluff, MO
Jan 26 - Jan 27
Per night/room
Auburn Place Hotel And Suites
Jan 26 - Jan 27
Per night/room
Pear Tree Inn Sikeston
Top luxury Southeast Missouri hotel deals
Price for 1 night 2 adults*
Jan 31 - Feb 1
Per night/room
Super 8 by Wyndham Pevely
The desk clerk was friendly and helpful. The room was not clean, the floors (no carpeting) were not swept, the bathroom needed a good scrubbing, the hallway was not clean. Someone kept propping the back door (next to our room) open, even though there was a sign on the door stating it was locked and ...
Jan 26 - Jan 27
Per night/room
Motel 6 Poplar Bluff, MO
Was given a key to a room that was not even cleaned yet. A lot of suspicious activity going on with guests on the 3rd floor. People slammed doors all night. The most uncomfortable bed ever.
Feb 15 - Feb 16
Per night/room
Days Inn and Suites by Wyndham Sikeston
I didnt like that the front desk clerk was not smiling and that only one heater was in the room took a while for the rest of the room to get warm.And tje bathroom floor stayed cold
How much is a hotel room in Southeast Missouri?
Hotels in Southeast Missouri start at $51 per night. Prices and availability subject to change. Additional terms may apply.
Cheap Hotels in Southeast Missouri
Pack your bags—it’s time to embark on a getaway. Whether you’re craving a solo retreat or promising your family a vacation to remember, book one of the best hotels in Southeast Missouri. These hotels are located within easy access of the city’s hottest attractions and entertainment, so you won’t miss a beat while you’re in town. Spend the days exploring the local landmarks and the evenings getting to know the nightlife. After exploring the city from top to bottom, rest up at a hotel that speaks to you. Find the perfect place that matches your trip’s vibe, from a trendy boutique to family-friendly accommodations.
Allow us here at Travelocity to pair you with up Southeast Missouri hotels that suit your vacation preferences. Discover places with convenient on-site restaurants, around-the-clock service, and pools where your kids can make a splash. Some hotels may boast fitness rooms and spa services, while others feature game rooms and Wi-Fi access. To top it all off, you’ll score cheap hotels in Southeast Missouri that let you spend more on your activities and less on your lodging. Book and bundle your flight and hotel deals together today and save up to $537. It’s time to explore a new city, and break out of your routine.
Recent Southeast Missouri hotel reviews by fellow wanderers
- Hotels with Free Parking (65)
- Kid Friendly Hotels (60)
- Convention Center Hotels (50)
- Pet Friendly Hotels (48)
- Hotels with Pools (45)
- Golf Resorts & Hotels (28)
- Hotels with an Indoor Pool (26)
- Cheap Hotels (23)
- Hotels with Hot Tubs (22)
- Hotels with Bar (19)
- Hotel Wedding Venues (16)
- Spa Resorts & Hotels (14)
- Casino Resorts & Hotels (13)
- Luxury Hotels (12)
- Historic Hotels (10)
- Winery Hotels (7)
- Romantic Getaways & Hotels (5)
- Hotels with Balconies (5)
- Hotels with Waterslides (1)
- Ski Resorts and Hotels (1)
An attraction
- Hotels near Isle Casino Cape Girardeau
- Hotels near Lady Luck Casino
- Hotels near Ozark National Scenic Riverways
- Hotels near Southeast Missouri State University
- Hotels near Lake Wappapello
- Hotels near Taum Sauk Mountain State Park
- Hotels near Johnson's Shut-ins State Park
- Hotels near Hunter Valley Winery
- Hotels near Elephant Rocks State Park
- Hotels near The Book Bug
- Hotels near Bonne Terre Mine
- Hotels near Delmo Park
- Hotels near Trail of Tears State Park
- Hotels near Echo Bluff State Park
- Hotels near National Shrine of Our Lady of the Miraculous Medal
- Hotels near Pickle Springs Natural Area
- Hotels near Rocky Falls
- Hotels near Alley Spring & Mill
- Hotels near Crown Valley Winery
- Hotels near Current River State Park
- Hotels near Hemingway Center
- Hotels near eDen Spa & Salon
- Hotels near Powder Mill Cave Natural Area
- Hotels near Missouri National Guard Armory
- Hotels near Hayti Pentecostal Holiness Church
- Hotels near Alley Spring Grist Mill Historic Site
- Hotels near Horseshoe Bend
- Hotels near Sikeston Depot Museum
- Hotels near St. Joe State Park
- Hotels near Kennett Country Club
- Hotels near Hayti Park
- Hotels near Crown Pointe Golf Club
- Hotels near Perryville Country Club
- Hotels near Twin Oaks Vineyard & Winery
- Hotels near College of the Ozarks
- Hotels near K Bridge Recreation Area
- Hotels near Caruthersville Public Library
- Hotels near St. James Catholic Church
- Hotels near Stoddard County Civil War Memorial Cemetery
- Hotels near Cave Vineyard
- Cape Girardeau Hotels
- Chesterfield Hotels
- Richmond Heights Hotels
- Poplar Bluff Hotels
- Arnold Hotels
- Belleville Hotels
- Fenton Hotels
- Dyersburg Hotels
- Cuba Hotels
- Frontenac Hotels
- Eureka Hotels
- Southeastern United States Hotels
- Festus Hotels
- Kirkwood Hotels
- Salem Hotels
- Wildwood Hotels
- Brentwood Hotels
- Sullivan Hotels
- East St. Louis Hotels
- Southern Illinois Hotels
- Jackson Hotels
- Paragould Hotels
- Anna Hotels
- Ste Genevieve Hotels
- St. Clair Hotels
- Charleston Hotels
- Pacific Hotels
- Pocahontas Hotels
- Southwest Missouri Hotels
- Ballwin Hotels
- Tiptonville Hotels
- Valley Park Hotels
- Northern Arkansas Hotels
- Dexter Hotels
- Town and Country Hotels
More ways to wander Southeast Missouri
- Flights to Southeast Missouri
The best fares to get you there
- Southeast Missouri Vacation Rentals
Great Deals on Alternative Accommodations
- Southeast Missouri Car Rentals
Affordable cars to get you around town
- Southeast Missouri Vacations
Save more by combining flights, hotels and cars
Most popular
-
- Hotels in St. Louis
- Hotels in Kansas City
- Hotels in Branson
- Extended Stay Hotels Kansas City
- Hotels with Hot Tubs in Kansas City
- Extended Stay Hotels Branson
- Waterpark Hotels and Resorts in Branson
- Extended Stay America Springfield - South
- Drury Inn & Suites St. Louis Fenton
- Hotels in Springfield
- Hotels near Highway 76 Strip
- Kid Friendly Hotels in Branson
- Hotels with Hot Tubs in St. Louis
- Hotels in Power and Light District
- Drury Inn & Suites Springfield, MO
- Drury Inn & Suites Hotels in St. Charles
- Hotels in Mexico
