Find and compare business hotels in Southeast Missouri, MO from $62

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Top Southeast Missouri Convention Center Hotels

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

2.5 out of 5
3253 William Street, Cape Girardeau, MO
Free Cancellation
The price is $117 per night
$117
per night
May 1 - May 2
A full-service spa and an indoor pool are featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public ...
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3 out of 5
225 Drury Lane, Jackson, MO
Free Cancellation
Reserve now, pay when you stay
The price is $94 per night
$94
per night
May 5 - May 6
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the spa tub and ...
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
The price is $90 per night
$90
per night
Apr 28 - Apr 29
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
The price is $108 per night
$108
per night
Apr 28 - Apr 29
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the spa tub and ...
Microtel Inn & Suites by Wyndham Sainte Genevieve

Microtel Inn & Suites by Wyndham Sainte Genevieve

2.5 out of 5
21958 Hwy 32, Ste Genevieve, MO
Free Cancellation
Reserve now, pay when you stay
The price is $87 per night
$87
per night
Apr 28 - Apr 29
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
The price is $70 per night
$70
per night
Apr 28 - Apr 29
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Auburn Place Hotel And Suites

Auburn Place Hotel And Suites

2.5 out of 5
3265 William St, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
The price is $70 per night
$70
per night
Apr 25 - Apr 26
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the free ...
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel

Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel

2.5 out of 5
115 Hospitality Dr, Sikeston, MO
Free Cancellation
The price is $119 per night
$119
per night
May 5 - May 6
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
The price is $98 per night
$98
per night
Apr 25 - Apr 26
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour ...
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St, Farmington, MO
Free Cancellation
Reserve now, pay when you stay
The price is $62 per night
$62
per night
May 12 - May 13
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
The price is $64 per night
$64
per night
May 11 - May 12
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...
Quality Inn Festus

Quality Inn Festus

3 out of 5
1200 W Gannon Dr, Festus, MO
The price is $71 per night
$71
per night
May 10 - May 11
This hotel features an indoor pool and a gym. Families will appreciate the arcade/game room and barbecue grills. Relax with a drink at the bar/lounge and enjoy ...
Don't see what you're looking for?
See all available properties in Southeast Missouri
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Conference Hotels in Southeast Missouri

Is your boss sending you off to Southeast Missouri for an important business meeting? Or maybe you're in town to attend a big conference? Travelocity's wide range of Southeast Missouri conference hotels are here to fulfill all of your business travel needs.

Whether you're planning a large, company-wide meeting or a small board meeting, the Southeast Missouri business hotels have you covered. These properties cater to business travelers with in-room Wi-Fi, work desks, and meeting rooms of varying sizes. Grab a drink at the lobby bar to mingle with co-workers you only see once a year or buy a drink for a potential new client. You can also use the on property fitness center to blow off some steam before your big presentation. You're guaranteed to impress your boss when you book a stay at one of Travelocity's Southeast Missouri conference hotels.

Relax in the comfortable rooms and crush your work presentation knowing you got the best deal on your business hotel in Southeast Missouri. Book your accommodations today and experience the value and customer service of Travelocity.

Southeast Missouri hotels essential information

Accommodation
559 hotels
Lowest Price
$62
Highest Price
$119
Popular hotels
Pear Tree Inn Sikeston, Auburn Place Hotel And Suites, Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel, Drury Inn & Suites Jackson MO, Best Western Plus Sikeston, Drury Inn & Suites Cape Girardeau, Microtel Inn & Suites by Wyndham Sainte Genevieve, Pear Tree Inn Cape Girardeau West, Quality Inn Festus, Baymont Inn and Suites by Wyndham Farmington, MO, Days Inn and Suites by Wyndham Sikeston, Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel

Recent Southeast Missouri hotel reviews by fellow wanderers

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Room was well kept"
A verified traveler stayed at Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston

Explore more Convention Center Hotels

Types of hotels

Hotels near…

Hotels by star rating

Areas of Southeast Missouri

Popular Convention Center Hotels Destinations