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Featured Mira Mesa 4 Star Hotels

Omni San Diego Hotel $127
Omni San Diego Hotel

Omni San Diego Hotel

675 L St, San Diego, CA
     
    4.4
    of 5, from 47 reviews
    4.0 out of 5.0 Stars

    This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour fitness center. Families will appreciate the onsite laundry facilities and in-room childcare. Traveling on business? Take advantage of the business center, express check-out, and valet parking.

    Hotel Republic San Diego, Autograph Collection $89
    Hotel Republic San Diego, Autograph Collection

    Hotel Republic San Diego, Autograph Collection

    421 W B St, San Diego, CA
       
      4.4
      of 5, from 8 reviews
      4.0 out of 5.0 Stars

      This boutique hotel's 2 restaurants, 2 bars/lounges, and 24-hour fitness center are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a rooftop terrace on site, and a 24-hour front desk and a coffee shop are also provided.

      Hilton San Diego Bayfront $98
      Hilton San Diego Bayfront

      Hilton San Diego Bayfront

      1 Park Blvd, San Diego, CA
         
        4.3
        of 5, from 116 reviews
        4.0 out of 5.0 Stars

        A full-service spa, a health club, and a restaurant are all featured at this smoke-free hotel. Bring the family and enjoy the waterslide and kid-friendly dining. Relax with a drink at one of the 2 bars/lounges and get perks like free WiFi.

        Marriott Marquis San Diego Marina $129
        Marriott Marquis San Diego Marina

        Marriott Marquis San Diego Marina

        333 W Harbor Dr, San Diego, CA
           
          4.3
          of 5, from 72 reviews
          4.0 out of 5.0 Stars

          This smoke-free hotel features a full-service spa, a marina, and 3 restaurants. Family-friendly amenities include a children's pool and kid-friendly dining, along with hiking/biking trails. Enjoy the 2 outdoor pools and perks like free WiFi.

          Hilton San Diego Mission Valley $97
          Hilton San Diego Mission Valley

          Hilton San Diego Mission Valley

          901 Camino Del Rio S, San Diego, CA
             
            4.2
            of 5, from 41 reviews
            4.0 out of 5.0 Stars

            This hotel features an outdoor pool, a 24-hour fitness center, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. There's a spa tub on site, and laundry facilities and concierge services are also offered.

            Manchester Grand Hyatt San Diego $108
            Manchester Grand Hyatt San Diego

            Manchester Grand Hyatt San Diego

            1 Market Pl, San Diego, CA
               
              4.2
              of 5, from 125 reviews
              4.0 out of 5.0 Stars

              A full-service spa, 6 restaurants, and 2 outdoor pools are all featured at this eco-friendly hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Unwind with drinks at one of the 3 bars/lounges or the poolside bar and make the most of the 2 outdoor tennis courts.

              Hyatt Regency Mission Bay Spa and Marina $98
              Hyatt Regency Mission Bay Spa and Marina

              Hyatt Regency Mission Bay Spa and Marina

              1441 Quivira Rd, San Diego, CA
                 
                4.2
                of 5, from 5 reviews
                4.0 out of 5.0 Stars

                A full-service spa, a marina, and 3 outdoor pools are all featured at this smoke-free resort. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. There's a restaurant and a poolside bar for dining and drinks, and also a health club on site.

                Intercontinental San Diego $137
                Intercontinental San Diego

                Intercontinental San Diego

                901 Bayfront Court, San Diego, CA
                   
                  4.2
                  of 5, from 12 reviews
                  4.0 out of 5.0 Stars

                  This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour fitness center. Traveling on business? Take advantage of the 15 conference rooms, 24-hour business center, and valet parking. Relax with a drink at one of the 3 bars/lounges and get perks like free WiFi.

                  Hard Rock Hotel San Diego $135
                  Hard Rock Hotel San Diego

                  Hard Rock Hotel San Diego

                  207 5th Ave, San Diego, CA
                     
                    4.1
                    of 5, from 87 reviews
                    4.0 out of 5.0 Stars

                    A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. With 2 coffee shops/cafés, poolside bar, and bar/lounge, there are plenty of spots to dine and unwind.

                    Paradise Point Resort & Spa $110
                    Paradise Point Resort & Spa

                    Paradise Point Resort & Spa

                    1404 Vacation Rd, San Diego, CA
                       
                      4.0
                      of 5, from 33 reviews
                      4.0 out of 5.0 Stars

                      This smoke-free resort features a full-service spa, a marina, and 3 restaurants. Families will appreciate the mini golf, onsite laundry facilities, and supervised childcare. Traveling on business? Take advantage of the business center, conference center, and conference space.

                      Sheraton San Diego Hotel and Marina $79
                      Sheraton San Diego Hotel and Marina

                      Sheraton San Diego Hotel and Marina

                      1380 Harbor Island Dr, San Diego, CA
                         
                        3.8
                        of 5, from 166 reviews
                        4.0 out of 5.0 Stars

                        This smoke-free hotel features a full-service spa, a marina, and 6 restaurants. Traveling on business? Take advantage of the 62 conference rooms, 24-hour business center, and free airport shuttle. Enjoy a meal in one of the 2 coffee shops/cafés and perks like free WiFi.

                        Wyndham San Diego Bayside $120
                        Wyndham San Diego Bayside

                        Wyndham San Diego Bayside

                        1355 N Harbor Drive, San Diego, CA
                           
                          3.7
                          of 5, from 169 reviews
                          4.0 out of 5.0 Stars

                          This smoke-free hotel includes 2 restaurants, an outdoor pool, and a fitness center. Traveling on business? Take advantage of the business center, express check-out, and free airport shuttle. Unwind with a drink at the bar/lounge and enjoy perks like a free cruise terminal shuttle.

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                          *Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.