Book Hotels in Defiance, Missouri

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Tonight

Sep 24 - Sep 25

Tomorrow night

Sep 25 - Sep 26

Next weekend

Sep 29 - Oct 1

Most frequently booked Defiance hotels

Sonesta ES Suites St. Louis - Chesterfield

15431 Conway Rd, Chesterfield, MO

Free Cancellation

Reserve now, pay when you stay

12.28 mi from city center

$88

per night

Oct 2 - Oct 3

This hotel features a 24-hour gym and a seasonal outdoor pool. Guests will appreciate free perks like free self parking and WiFi in public areas. A business center, a garden, and express check-out are also on offer.

Pool

Pet friendly

Hollywood Casino & Hotel St. Louis

777 Casino Center Drive, Maryland Heights, MO

Free Cancellation

Reserve now, pay when you stay

18.13 mi from city center

$97

per night

Sep 26 - Sep 27

This hotel features a casino, a nightclub, and 7 restaurants. Traveling for business? Take advantage of the 24-hour business center, express check-out, and conference space. Relax with a drink at one of the 3 bars/lounges and enjoy perks like free self parking.

Parking included

Restaurant

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

1970 Craig Rd, Maryland Heights, MO

Free Cancellation

Reserve now, pay when you stay

18.61 mi from city center

$68

per night

Sep 25 - Sep 26

A gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like on-the-go breakfast and WiFi in public areas. A 24-hour business center, a library, and free newspapers are also on offer.

Pool

Breakfast included

The Wildwood Hotel

2801 Fountain Pl, Wildwood, MO

Free Cancellation

Reserve now, pay when you stay

8.76 mi from city center

$80

per night

Oct 2 - Oct 3

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the spa tub and free perks like continental breakfast and free self parking.

Pool

Hot Tub

Best Western Plus The Charles Hotel

1425 South 5th Street, St. Charles, MO

Free Cancellation

Reserve now, pay when you stay

18.08 mi from city center

$87

per night

Oct 2 - Oct 3

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Pool

Breakfast included

Embassy Suites by Hilton St. Louis St. Charles

2 Convention Center Plz, St. Charles, MO

Free Cancellation

Reserve now, pay when you stay

17.63 mi from city center

$136

per night

Sep 28 - Sep 29

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.

Pool

Breakfast included

Ameristar Casino Resort and Spa

1 Ameristar Blvd, St. Charles, MO

Free Cancellation

Reserve now, pay when you stay

18.31 mi from city center

$169

per night

Sep 25 - Sep 26

This luxury hotel features a casino, a full-service spa, and 5 restaurants. Enjoy the 2 spa tubs and indoor pool, and unwind with a drink at the poolside bar.

Pool

Hot Tub

Research Park Inn St Louis West – Chesterfield

32 Research Park Circle, St. Charles, MO

Free Cancellation

Reserve now, pay when you stay

7.2 mi from city center

$76

per night

Sep 25 - Sep 26

This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the spa tub and free perks like continental breakfast and free self parking.

Pool

Hot Tub

Drury Plaza Hotel St. Louis Chesterfield

355 Chesterfield Ctr, Chesterfield, MO

Free Cancellation

Reserve now, pay when you stay

11.78 mi from city center

$126

per night

Oct 1 - Oct 2

This hotel features an outdoor pool, an indoor pool, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top hotels in Defiance for Extended Stay

Craigshire Suites

1881 Craigshire Rd, Maryland Heights, MO

$59

per night

Sep 27 - Sep 28

7/10 Good! (1,060 reviews)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Defiance Hotel & Travel Guide\n

There isn't a big range of places to base yourself on Travelocity within a 6-mile (10-kilometer) distance of downtown Defiance. We recommend you book as soon as you're ready if you want to stay close to the action.

The Holiday Inn St. Louis West Six Flags, Missouri, which is the closest Travelocity-listed place to stay, sits 13 miles (21 kilometers) from downtown Defiance. Instead, you could think about the Residence Inn By Marriott St Louis Chesterfield, located in Missouri, which is 14 miles (22 kilometers) from the town center.

6 miles (10 kilometers) away from the heart of Defiance, you will find the Staybridge Suites O'Fallon Chesterfield. Alternatively, the Residence Inn by Marriott O'Fallon is 6 miles (10 kilometers) away. Some other options in the Defiance area include the Holiday Inn Express St. Louis West - O'Fallon and the Hilton Garden Inn St. Louis/O'Fallon.

If you have the time, why not broaden your horizons and get to know the other sights located around St. Louis - Northeast Missouri while you are in Defiance? Photographers will love St. Louis - Northeast Missouri's prairies. While you're at it, go to a few of its history museums. Sporty visitors may also try mountain biking, hiking and cycling in the region.

Downtown St. Louis is 30 miles (52 kilometers) to the east of Defiance and boasts Old Post Office and Scott Joplin House State Historic Site. The Four Seasons Hotel St Louis and Grand Center Inn are some of the great hotel choices in Downtown St. Louis. Or, you could stay in North MetroEast, 45 miles (69 kilometers) to the east of Defiance, where you can pick from the Hampton Inn Suites St LouisEdwardsville and Comfort Inn and Conference Center. If you're staying in North MetroEast, set aside some time to check out the Gardens at SIUE and Edwardsville Arts Center.

If enjoying sport is never far from your mind, pay a visit to Busch Stadium, located 35 miles (53 kilometers) to the east of Defiance. Book a hotel surrounded by the sporting action at the The Westin St. Louis or the Embassy Suites St. Louis - Downtown.

If you are planning on arriving through Lambert-St. Louis International Airport, you might like to stay at Marriott St. Louis Airport, or Holiday Inn St. Louis-Airport, both of which are a short distance away.

Defiance hotels essential information

Accommodation	745 hotels
Lowest Price	$59
Highest Price	$169
Popular hotels	Sonesta ES Suites St. Louis - Chesterfield, Hollywood Casino & Hotel St. Louis, Days Inn and Suites by Wyndham St. Louis/Westport Plaza, The Wildwood Hotel, Best Western Plus The Charles Hotel, Embassy Suites by Hilton St. Louis St. Charles, Ameristar Casino Resort and Spa, Research Park Inn St Louis West – Chesterfield, Drury Plaza Hotel St. Louis Chesterfield

Frequently asked questions

What are the top kid-friendly hotels in Defiance?

Family getaways are where lifelong memories are made, but it’s no secret that traveling with young ones can be difficult. These kid-friendly Defiance hotels come with perks designed to keep guests of all ages comfortable and happy: The Ruebling House Historic Defiance Apartment! will help make your getaway the best one yet. It comes with plenty of nice little touches, such as free WiFi and extra bedding. Otherwise, spend your Defiance trip at ‘The Reubling House’ - Modern-Rustic Cabin!. Make the most of a barbecue grill, internet access and more here.

Where can I find cheap hotels in Defiance?

At Travelocity you’ll find really nice hotels in Defiance at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Defiance rather than in Defiance. We may find you even better rates, too.

How do I find the best Defiance hotel deals?

Simple! On Travelocity, look through the fantastic offers we’ve already found in Defiance then use our filters to find a great deal that’s perfect for you. Enter your travel dates, select the number of rooms you need, and we’ll do the rest. You can get great discounts on flights and car hire, too, when you bundle.

How much does it cost to stay in a hotel in Defiance?

The cheapest hotel in Defiance is $59. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel’s location. Prices and availability are subject to change. Additional terms apply.

How many hotels are in Defiance?

There are 745 hotels in Defiance on Travelocity.

What are the best hotels in Defiance?

Defiance has so many great hotels to choose from at Travelocity — and it’s so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Defiance for you!

When is the best time to visit Defiance?

If you want the joy of a fun-filled trip in peak season, visit Defiance during March, April and May. If you’d prefer the peace of off-season, book a stay during quieter months, such as December, January and February.

When is the cheapest time to stay in Defiance?

Based on historic data is usually the cheapest month to visit Defiance. However, we have incredible deals all year round, so we’re confident you’ll find a room in your budget whenever you choose to travel.

Are there any great family-friendly hotels in Defiance?

There are multiple hotels in Defiance that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We’ve got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Defiance. We have plenty of kid-friendly hotels in Defiance to choose from on Travelocity!

Why book a hotel in Defiance through Travelocity?

Because we have the top hotels in Defiance! We want to help you travel more and worry less. That’s why we’ve put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you’re getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!

How do I cancel my hotel booking in Defiance on Travelocity?

Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.