Book Hotels in Upstate South Carolina, SC

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top hotels in Upstate South Carolina for Extended Stay

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Seize your some day

Cheap Hotels in Upstate South Carolina

Pack your bags—it’s time to embark on a getaway. Whether you’re craving a solo retreat or promising your family a vacation to remember, book one of the best hotels in Upstate South Carolina. These hotels are located within easy access of the city’s hottest attractions and entertainment, so you won’t miss a beat while you’re in town. Spend the days exploring the local landmarks and the evenings getting to know the nightlife. After exploring the city from top to bottom, rest up at a hotel that speaks to you. Find the perfect place that matches your trip’s vibe, from a trendy boutique to family-friendly accommodations.

Allow us here at Travelocity to pair you with up Upstate South Carolina hotels that suit your vacation preferences. Discover places with convenient on-site restaurants, around-the-clock service, and pools where your kids can make a splash. Some hotels may boast fitness rooms and spa services, while others feature game rooms and Wi-Fi access. To top it all off, you’ll score cheap hotels in Upstate South Carolina that let you spend more on your activities and less on your lodging. Book and bundle your flight and hotel deals together today and save $$$. It’s time to explore a new city, and break out of your routine.

Upstate South Carolina hotels essential information

Accommodation
2,464 hotels
Lowest Price
$55
Highest Price
$169
Popular hotels
Hilton Greenville, Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd, an IHG Hotel, Best Western Plus Greenville I-385 Inn & Suites, La Quinta Inn & Suites by Wyndham Greenville Haywood, Hyatt Regency Greenville, Hotel Hartness, Comfort Inn Greenville - Haywood Mall, Hyatt Place Greenville/Downtown, Cambria Hotel Greenville

Recent Upstate South Carolina hotel reviews by fellow wanderers