Book Hotels in South Carolina Midlands, SC

Wander wisely with the Travelocity Price Match Guarantee

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check hotel availability in South Carolina Midlands

Tonight
Check prices in South Carolina Midlands for tonight, Mar 19 - Mar 20
Tomorrow night
Check prices in South Carolina Midlands for tomorrow night, Mar 20 - Mar 21
This weekend
Check prices in South Carolina Midlands for this weekend, Mar 22 - Mar 24
Next weekend
Check prices in South Carolina Midlands for next weekend, Mar 29 - Mar 31

Most frequently booked South Carolina Midlands hotels

Don't see what you're looking for?
See all available properties in South Carolina Midlands
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top family friendly South Carolina Midlands hotel deals

Top cheap South Carolina Midlands hotel deals

Top hotels in South Carolina Midlands for Extended Stay

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Seize your some day

Cheap Hotels in South Carolina Midlands

Pack your bags—it’s time to embark on a getaway. Whether you’re craving a solo retreat or promising your family a vacation to remember, book one of the best hotels in South Carolina Midlands. These hotels are located within easy access of the city’s hottest attractions and entertainment, so you won’t miss a beat while you’re in town. Spend the days exploring the local landmarks and the evenings getting to know the nightlife. After exploring the city from top to bottom, rest up at a hotel that speaks to you. Find the perfect place that matches your trip’s vibe, from a trendy boutique to family-friendly accommodations.

Allow us here at Travelocity to pair you with up South Carolina Midlands hotels that suit your vacation preferences. Discover places with convenient on-site restaurants, around-the-clock service, and pools where your kids can make a splash. Some hotels may boast fitness rooms and spa services, while others feature game rooms and Wi-Fi access. To top it all off, you’ll score cheap hotels in South Carolina Midlands that let you spend more on your activities and less on your lodging. Book and bundle your flight and hotel deals together today and save $$$. It’s time to explore a new city, and break out of your routine.

South Carolina Midlands hotels essential information

Accommodation
2,640 hotels
Lowest Price
$48
Highest Price
$179
Popular hotels
La Quinta Inn by Wyndham Columbia NE/Fort Jackson, Hilton Garden Inn Columbia/Harbison, Wyndham Garden Columbia/Ft. Jackson, Howard Johnson by Wyndham Florence, Graduate Columbia, S.C., Cambria Hotel Columbia Downtown The Vista, Marriott Columbia, Park Inn by Radisson Florence, SC, Lexington Inn and Suites

Recent South Carolina Midlands hotel reviews by fellow wanderers