Book a hotel near Florida Keys National Marine Sanctuary, Key West

Wander Wisely with the Travelocity Price Match Guarantee

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Hotels near Florida Keys National Marine Sanctuary

Angelina Guest House

Angelina Guest House

2.5 out of 5
302 Angela St, Key West, FL, 33040
0.3 mi from Florida Keys National Marine Sanctuary
Get rates
An outdoor pool is featured at this guesthouse, along with free WiFi in public areas and a garden. Enjoy the free continental breakfast each morning. Luggage storage is also provided.
Lazy River Pool, Enchanting Garden, Old Town Key West, Free WiFi, Bikes & Parkin

Lazy River Pool, Enchanting Garden, Old Town Key West, Free WiFi, Bikes & Parkin

Key West, FL
0.35 mi from Florida Keys National Marine Sanctuary
Get rates
A garden is available at this vacation home.
Weatherstation Inn

Weatherstation Inn

2.5 out of 5
57 Front St, Key West, FL, 33040
Free Cancellation
Reserve now, pay when you stay
0.36 mi from Florida Keys National Marine Sanctuary
The price is $199 per night
An outdoor pool, free self parking, and concierge services are featured at this bed & breakfast. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A terrace and free newspapers are also provided.
Coco Plum Inn

Coco Plum Inn

3 out of 5
611 Whitehead Street, Key West, FL, 33040
0.38 mi from Florida Keys National Marine Sanctuary
The price is $239 per night
An outdoor pool is featured at this guesthouse, along with free WiFi in public areas and a terrace. A garden, luggage storage, and concierge services are also on offer.
Carey's Corner #10 // Second Floor Small Studio at The Galleria

Carey's Corner #10 // Second Floor Small Studio at The Galleria

Key West, FL
0.38 mi from Florida Keys National Marine Sanctuary
The price is $205 per night
Stay at this apartment in Key West. Enjoy free WiFi, a patio, and a TV. Popular attractions Southernmost Point and Duval Street are located nearby. Discover genuine guest reviews for Carey's Corner #10 // Second Floor Small Studio at The Galleria, in Old Town Key West neighborhood, along with the latest prices and availability – book now.
Salvador's Suite #4 // Small Studio in Bahama Village at The Galleria

Salvador's Suite #4 // Small Studio in Bahama Village at The Galleria

Key West, FL
0.38 mi from Florida Keys National Marine Sanctuary
The price is $215 per night
Stay at this apartment in Key West. Enjoy free WiFi, a patio, and a TV. Popular attractions Southernmost Point and Duval Street are located nearby. Discover genuine guest reviews for Salvador's Suite #4 // Small Studio in Bahama Village at The Galleria, in Old Town Key West neighborhood, along with the latest prices and availability – book now.
Kimpton Lighthouse Hotel, an IHG Hotel

Kimpton Lighthouse Hotel, an IHG Hotel

3.5 out of 5
902 Whitehead St, Key West, FL, 33040
Free Cancellation
Reserve now, pay when you stay
0.41 mi from Florida Keys National Marine Sanctuary
The price is $215 per night
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. WiFi in public areas is free. Self parking, a terrace, and a garden are also offered.
The Cabana Inn Key West - Adults Only

The Cabana Inn Key West - Adults Only

3 out of 5
413 Applerouth Lane, Key West, FL, 33040
Free Cancellation
Reserve now, pay when you stay
0.42 mi from Florida Keys National Marine Sanctuary
The price is $160 per night
This guesthouse features an outdoor pool and a spa tub. WiFi in public areas is free. Self parking, a business center, and a terrace are also offered.
Duval House

Duval House

3 out of 5
815 Duval St, Key West, FL, 33040
0.48 mi from Florida Keys National Marine Sanctuary
The price is $174 per night
An outdoor pool, self parking, and concierge services are featured at this bed & breakfast. A terrace, a garden, and a picnic area are also on offer.
Crowne Plaza Key West-La Concha

Crowne Plaza Key West-La Concha

4 out of 5
430 Duval St, Key West, FL, 33040
Free Cancellation
0.51 mi from Florida Keys National Marine Sanctuary
The price is $269 per night
This hotel features 2 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Relax with a drink at one of the 3 bars/lounges and enjoy perks like free self parking.
Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West

4 out of 5
245 Front Street, Key West, FL, 33040
Free Cancellation
Reserve now, pay when you stay
0.57 mi from Florida Keys National Marine Sanctuary
The price is $278 per night
A marina, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 11 conference rooms, as well as the 24-hour business center and free WiFi in public areas. Enjoy the outdoor pool and visit the 3 bars/lounges and poolside bar for drinks.
Southernmost Beach Resort

Southernmost Beach Resort

4 out of 5
1319 Duval Street, Key West, FL, 33040
Free Cancellation
Reserve now, pay when you stay
0.7 mi from Florida Keys National Marine Sanctuary
The price is $314 per night
This hotel features a full-service spa, 3 outdoor pools, and a restaurant. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Traveling for business? Take advantage of the 24-hour business center, laundry service, and conference space.
Don't see what you're looking for?
See all available properties in Florida Keys National Marine Sanctuary
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels Close to Florida Keys National Marine Sanctuary

Your next vacation is around the corner. The kids are out of school, you and the spouse have two weeks off, and it’s about time to get the heck out of dodge. You must experience the culture and see the sights. Book your stay Florida Keys National Marine Sanctuary hotels with us at Travelocity and enjoy the trip of a lifetime.

Finally, you can stay near the sites you’ve only read about in books. Now they are next door. Start fresh in the morning with the amazing views from your balcony. Then hop on any number of tour buses and take postcard-worthy pictures of the attractions you once thought couldn’t be real, but now you find them through your lens. Hotels near Florida Keys National Marine Sanctuary will offer you the best in prices, activities, amenities, dining, and nightlife.

You may not want to imitate the Griswald’s--that’s been done one too many times—but you do want to have a memorable trip. With Travelocity’s long list of cheap hotels near Florida Keys National Marine Sanctuary, you’re sure to find the perfect place to stay within your preferred budget. We’ll match a lower price and refund the difference. Book now and let us make your next vacation the easiest of your life.

Recent Florida Keys National Marine Sanctuary hotel reviews by fellow wanderers

  • Duval House

    Duval House

    5 out of 5
    Posted 1 month ago
    travelocity Verified Review
    "Gorgeous property! Beds are wonderfully comfortable. Quiet location even though it’s walking distance to everything. Very clean. If I could have had one with, I would have liked the housekeeper to sweep, empty trash, and make the bed every two to three days of our stay. "
    A verified traveler stayed at Duval House
    Duval House
  • Crowne Plaza Key West-La Concha

    Crowne Plaza Key West-La Concha

    5 out of 5
    Posted 2 months ago
    travelocity Verified Review
    "Central location, great staff "
    A verified traveler stayed at Crowne Plaza Key West-La Concha
    Crowne Plaza Key West-La Concha
  • Southernmost Beach Resort

    Southernmost Beach Resort

    5 out of 5
    Posted 3 months ago
    travelocity Verified Review
    "This hotel was in a great location to the beach and fun in Key West! "
    A verified traveler stayed at Southernmost Beach Resort
    Southernmost Beach Resort
  • Weatherstation Inn

    Weatherstation Inn

    5 out of 5
    Posted 4 months ago
    travelocity Verified Review
    "Beautiful location. Quiet at night but close to everything."
    A verified traveler stayed at Weatherstation Inn
    Weatherstation Inn
  • Angelina Guest House

    Angelina Guest House

    3 out of 5
    Posted 4 months ago
    travelocity Verified Review
    "We’ve been staying at this property for over 10 years. We’ve always been warmly welcome. The checkin staff now is not friendly and very inattentive.it was like we were a bother. We have never encountered this at the Angelina. AND to top it all off the famous cinnamon buns were replaced with a muffin!!!!! Angelina cinnamon buns were homemade freshly daily. The muffins were awful as was the stale bread. The toaster took forever to toast. We asked to upgrade to a larger room ( we were willing to pay for the upgrade) and was told the room was occupied. NO one was in that room the time we were there. "
    A verified traveler from Plainsboro stayed at Angelina Guest House
    Angelina Guest House
  • Salvador's Suite #4 // Small Studio in Bahama Village at The Galleria

    Salvador's Suite #4 // Small Studio in Bahama Village at The Galleria

    4 out of 5
    Posted 4 months ago
    travelocity Verified Review
    "Sweet little room in a nice quiet location. Small problem with a couple cleanliness issues but the management responded promptly. "
    A verified traveler stayed at Salvador's Suite #4 // Small Studio in Bahama Village at The Galleria
    Salvador's Suite #4 // Small Studio in Bahama Village at The Galleria