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Featured Key West 4 Star Hotels

$199
The Marker Waterfront Resort Key West

The Marker Waterfront Resort Key West

4.0 out of 5.0 200 William Street, Key West, FL
4.7/5
(38 Reviews)
This smoke-free hotel features 3 outdoor pools, a fitness center, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a poolside bar on site, and a 24-hour front desk and concierge services are also provided.
$259
Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort

4.0 out of 5.0 Zero Duval St., Key West, FL
4.7/5
(109 Reviews)
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this romantic resort. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and valet parking. There's a poolside bar on site, and concierge services and free newspapers are also provided.
$289
Pier House Resort & Spa

Pier House Resort & Spa

4.0 out of 5.0 1 Duval St, Key West, FL
4.7/5
(98 Reviews)
This romantic resort features a private beach, a full-service spa, and 2 restaurants. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like free self parking and WiFi in public areas.
$175
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

4.0 out of 5.0 5950 Peninsular Avenue, Key West, FL
4.6/5
(47 Reviews)
A marina, 6 outdoor pools, and a 24-hour fitness center are all featured at this smoke-free hotel. Business travelers can take advantage of the free WiFi in public areas. Enjoy a meal from the restaurant and perks like a free area shuttle.
$132
The Gates Hotel Key West

The Gates Hotel Key West

4.0 out of 5.0 3824 N Roosevelt Blvd, Key West, FL
4.3/5
(30 Reviews)
This hotel features an outdoor pool, a fitness center, and a restaurant. Relax with a drink at the poolside bar and enjoy perks like free self parking and free WiFi. There's a bar/lounge on site, and laundry facilities and concierge services are also provided.
$249
Southernmost Beach Resort

Southernmost Beach Resort

4.0 out of 5.0 1319 Duval Street, Key West, FL
4.3/5
(124 Reviews)
This romantic hotel features a full-service spa, 3 outdoor pools, and a restaurant. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Traveling for business? Take advantage of the 24-hour business center, laundry service, and conference space.
$268
Margaritaville Key West Resort & Marina

Margaritaville Key West Resort & Marina

4.0 out of 5.0 245 Front Street, Key West, FL
4.2/5
(20 Reviews)
A marina, a 24-hour fitness center, and a restaurant are all featured at this hotel. Traveling on business? Take advantage of the 4 conference rooms, 24-hour business center, and valet parking. Relax with a drink at one of the 3 bars/lounges and get perks like free WiFi.
$169
Parrot Key Hotel & Villas

Parrot Key Hotel & Villas

4.0 out of 5.0 2801 N Roosevelt Blvd, Key West, FL
4.2/5
(41 Reviews)
This smoke-free resort features 4 outdoor pools, a fitness center, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Unwind with a drink at the poolside bar and enjoy perks like a free area shuttle.
$132
24 North Hotel Key West

24 North Hotel Key West

4.0 out of 5.0 3820 North Roosevelt Boulevard, Key West, FL
4.2/5
(46 Reviews)
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a fitness center. Business travelers can take advantage of the free WiFi in public areas. Relax with a drink at one of the 2 bars/lounges and enjoy perks like free self parking.
$243
Crowne Plaza Key West-La Concha

Crowne Plaza Key West-La Concha

4.0 out of 5.0 430 Duval St, Key West, FL
4.1/5
(136 Reviews)
This romantic hotel features a golf course, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and free valet parking. Enjoy the outdoor pool and visit the 3 bars/lounges and poolside bar for drinks.
$290
Casa Marina Key West, A Waldorf Astoria Resort

Casa Marina Key West, A Waldorf Astoria Resort

4.0 out of 5.0 1500 Reynolds Street, Key West, FL
4/5
(169 Reviews)
A full-service spa, 3 restaurants, and 2 outdoor pools are all featured at this romantic resort. Relax with sun loungers and beach umbrellas, and cool off with a drink at the beachside bar. Families will appreciate supervised childcare, along with kayaking.
$129
The Perry Hotel Key West

The Perry Hotel Key West

4.0 out of 5.0 7001 Shrimp Road, Key West, FL
3.7/5
(15 Reviews)
A marina, 3 restaurants, and 2 outdoor pools are all featured at this smoke-free resort. Unwind with a drink at one of the 2 poolside bars and enjoy free perks like free self parking and a shopping center shuttle. There's a 24-hour fitness center on site, and laundry facilities and concierge services are also offered.

Recently booked Key West hotels

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4 Star Hotels Key West

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Key West 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Key West will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Key West, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Key West Hotel Reviews By Fellow Wanderers

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.